Literature DB >> 6093998

Latent beta-transforming growth factor in nontransformed and Kirsten sarcoma virus-transformed normal rat kidney cells, clone 49F.

R Pircher, D A Lawrence, P Jullien.   

Abstract

Normal rat kidney cells of the clone 49F and their Ki-MSV-transformed counterparts spontaneously release the same transforming growth factor (TGF) activity in an inactive form. By acidification followed by neutralization prior to assay, this TGF activity is unmasked and promotes anchorage-independent growth of the NRK-49F indicator cells in the presence of epidermal growth factor. The TGF activity released by both cell types has an apparent molecular weight of 9,000 under acidic conditions, does not compete for binding to epidermal growth factor receptors, is heat resistant but dithiothreitol and trypsin sensitive, and therefore is of the beta-TGF class.

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Year:  1984        PMID： 6093998

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  18 in total

1.  Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

Authors:  P J Sime; Z Xing; F L Graham; K G Csaky; J Gauldie
Journal:  J Clin Invest       Date:  1997-08-15       Impact factor: 14.808

2.  Growth factor interactions between mouse mammary cell lines cocultured in collagen gels.

Authors:  S Hamner; W Jones; J R Starkey; H L Hosick
Journal:  In Vitro Cell Dev Biol       Date:  1989-12

Review 3.  The Discovery and Early Days of TGF-β: A Historical Perspective.

Authors:  Harold L Moses; Anita B Roberts; Rik Derynck
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-07-01       Impact factor: 10.005

4.  Expression and secretion of type beta transforming growth factor by activated human macrophages.

Authors:  R K Assoian; B E Fleurdelys; H C Stevenson; P J Miller; D K Madtes; E W Raines; R Ross; M B Sporn
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

5.  Molecular cloning of the large subunit of transforming growth factor type beta masking protein and expression of the mRNA in various rat tissues.

Authors:  T Tsuji; F Okada; K Yamaguchi; T Nakamura
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

6.  Transforming growth factor beta-like activity in human hydrocele fluid.

Authors:  P K Saha; S Kanda; H Morimitsu; N Nishimura; H Kanetake; Y Saito
Journal:  Urol Res       Date:  1990

7.  Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.

Authors:  A B Glick; K C Flanders; D Danielpour; S H Yuspa; M B Sporn
Journal:  Cell Regul       Date:  1989-11

8.  Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3.

Authors:  Y J Bang; S J Kim; D Danielpour; M A O'Reilly; K Y Kim; C E Myers; J B Trepel
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

9.  Expression of transforming growth factor-beta 1 and its relation to endomysial fibrosis in progressive muscular dystrophy.

Authors:  M Yamazaki; S Minota; H Sakurai; K Miyazono; A Yamada; I Kanazawa; M Kawai
Journal:  Am J Pathol       Date:  1994-02       Impact factor: 4.307

10.  In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1.

Authors:  Jasimuddin Ahamed; Nathalie Burg; Keiji Yoshinaga; Christin A Janczak; Daniel B Rifkin; Barry S Coller
Journal:  Blood       Date:  2008-06-10       Impact factor: 22.113
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