Literature DB >> 6093178

Multiple sites of action for anxiogenic drugs: behavioural, electrophysiological and biochemical correlations.

S Pellow, S E File.   

Abstract

This review describes animal models of anxiety that are able to identify an anxiogenic drug effect. Evidence is reviewed for the anxiogenic action of several drugs that act at the GABA-benzodiazepine-chloride ionophore complex in the brain. The effects of their combinations with various other drugs thought to act at the same sites are discussed. The classification of these drugs on the basis of their behavioural profiles is compared with their classification based on biochemical and electrophysiological studies.

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Year:  1984        PMID： 6093178     DOI： 10.1007/bf00428536

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  101 in total

1.  Metrazol tolerance in a normal voluntser population; an investigation of the potential significance of abnormal findings.

Authors:  E RODIN
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1958-08

2.  Benzodiazepine receptors: differential interaction of benzodiazepine agonists and antagonists after photoaffinity labeling with flunitrazepam.

Authors:  H Möhler
Journal:  Eur J Pharmacol       Date:  1982-06-04       Impact factor: 4.432

3.  The proconvulsant and diazepam-reversing effects of ethyl-beta-carboline-3-carboxylate.

Authors:  N R Oakley; B J Jones
Journal:  Eur J Pharmacol       Date:  1980-12-05       Impact factor: 4.432

4.  GABA reduces binding of 3H-methyl beta-carboline-3-carboxylate to brain benzodiazepine receptors.

Authors:  C Braestrup; M Nielsen
Journal:  Nature       Date:  1981-12-03       Impact factor: 49.962

5.  Characterization of peripheral-type benzodiazepine binding sites in brain using [3H]Ro 5-4864.

Authors:  P J Marangos; J Patel; J P Boulenger; R Clark-Rosenberg
Journal:  Mol Pharmacol       Date:  1982-07       Impact factor: 4.436

6.  The picrotoxin-like action of a convulsant benzodiazepine, Ro5-3663.

Authors:  N L Harrison; M A Simmonds
Journal:  Eur J Pharmacol       Date:  1983-01-28       Impact factor: 4.432

7.  On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain.

Authors:  S E File; A R Green; D J Nutt; N D Vincent
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

8.  Benzodiazepine receptor-mediated experimental "anxiety" in primates.

Authors:  P T Ninan; T M Insel; R M Cohen; J M Cook; P Skolnick; S M Paul
Journal:  Science       Date:  1982-12-24       Impact factor: 47.728

9.  Ethyl beta-carboline-3-carboxylate shows differential benzodiazepine receptor interaction.

Authors:  M Nielsen; C Braestrup
Journal:  Nature       Date:  1980-08-07       Impact factor: 49.962

Review 10.  Convulsant/depressant site of action at the allosteric benzodiazepine-GABA receptor-ionophore complex.

Authors:  M K Ticku; G Maksay
Journal:  Life Sci       Date:  1983-12-12       Impact factor: 5.037
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  36 in total

Review 1.  Modeling anxiety in healthy humans: a key intermediate bridge between basic and clinical sciences.

Authors:  Christian Grillon; Oliver J Robinson; Brian Cornwell; Monique Ernst
Journal:  Neuropsychopharmacology       Date:  2019-06-21       Impact factor: 7.853

2.  RO 15-1788 does not influence postpartum aggression in lactating female rats.

Authors:  J Mos; B Olivier
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

3.  The effects of the benzodiazepine antagonist Ro 15-1788 on psychophysiological performance and subjective measures in normal subjects.

Authors:  A Higgitt; M Lader; P Fonagy
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

4.  The benzodiazepine antagonist CGS 8216 decreases both shocked and unshocked drinking in rats.

Authors:  D J Sanger
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 5.  Intrinsic actions of the benzodiazepine receptor antagonist Ro 15-1788.

Authors:  S E File; S Pellow
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

6.  Actions of the beta-carboline ZK 93426 in an animal test of anxiety and the holeboard: interactions with Ro 15-1788.

Authors:  S E File; S Pellow; L H Jensen
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

7.  GABAergic drugs and conflict behavior in the rat: lack of similarities with the actions of benzodiazepines.

Authors:  A Agmo; R Pruneda; M Guzmán; M Gutiérrez
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-09       Impact factor: 3.000

8.  Riluzole antagonizes the anxiogenic properties of the beta-carboline FG 7142 in rats.

Authors:  J M Stutzmann; P Cintrat; P M Laduron; J C Blanchard
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

9.  Proceedings of the British Pharmacological Society. 10th-18th September 1986. Abstracts.

Authors: 
Journal:  Br J Pharmacol       Date:  1986-12       Impact factor: 8.739

10.  The effects of an acute challenge with the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, on social inhibition in adolescent and adult male rats.

Authors:  Melissa Morales; Linda P Spear
Journal:  Psychopharmacology (Berl)       Date:  2013-09-17       Impact factor: 4.530
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