Literature DB >> 6091821

Epidermal growth factor receptors in human breast cancer.

R Pérez, M Pascual, A Macías, A Lage.   

Abstract

The capacity for specific binding of 125I-epidermal growth factor (EGF) was studied in crude membrane fractions from 95 human breast carcinomas. About 42% of the samples showed saturable, high affinity, specific binding of EGF. In 21% of the tumors we were able to demonstrate high (above 10 fmoles/mg protein) binding capacity. Moreover, high EGF receptor values were associated with a low content of estradiol receptor. These studies are related to the definition of new biochemical markers in human breast cancer.

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Year:  1984        PMID： 6091821     DOI： 10.1007/bf01806484

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  18 in total

1.  MSA and EGF receptors on sarcoma virus transformed cells and human fibrosarcoma cells in culture.

Authors:  G J Todaro; J E De Larco; S P Nissley; M M Rechler
Journal:  Nature       Date:  1977-06-09       Impact factor: 49.962

2.  Growth factors from murine sarcoma virus-transformed cells.

Authors:  J E de Larco; G J Todaro
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

3.  Standards for the assessment of estrogen receptors in human breast cancer. Report of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis, Amsterdam.

Authors: 
Journal:  Eur J Cancer       Date:  1973-05       Impact factor: 9.162

4.  Epidermal growth factor and a new derivative. Rapid isolation procedures and biological and chemical characterization.

Authors:  C R Savage; S Cohen
Journal:  J Biol Chem       Date:  1972-12-10       Impact factor: 5.157

5.  Stimulation of mammary carcinoma cell proliferation by epithelial growth factor in vitro.

Authors:  R W Turkington
Journal:  Cancer Res       Date:  1969-07       Impact factor: 12.701

6.  Epidermal growth factor receptors and effect of epidermal growth factor on growth of human breast cancer cells in long-term tissue culture.

Authors:  Y Imai; C K Leung; H G Friesen; R P Shiu
Journal:  Cancer Res       Date:  1982-11       Impact factor: 12.701

7.  The prognostic value of estrogen receptor determinations in patients with primary breast cancer: an update.

Authors:  P Furmanski; D E Saunders; S C Brooks; M A Rich
Journal:  Cancer       Date:  1980-12-15       Impact factor: 6.860

8.  Factors associated with prognosis in human breast cancer. III. Estradiol receptors and short term relapse.

Authors:  M R Pascual; A Macías; L Moreno; A Lage
Journal:  Neoplasma       Date:  1983       Impact factor: 2.575

9.  Factors associated with prognosis in human breast cancer. IV. Progesterone receptors and clinical factors.

Authors:  A Macías; M R Pascual; R Pérez; A Lage
Journal:  Neoplasma       Date:  1983       Impact factor: 2.575

10.  Relationship of presence of progesterone receptors to prognosis in early breast cancer.

Authors:  M F Pichon; C Pallud; M Brunet; E Milgrom
Journal:  Cancer Res       Date:  1980-09       Impact factor: 12.701
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  38 in total

Review 1.  Biochemical study of cyst fluid in human breast cystic disease: a review.

Authors:  C L Enriori; J E Novelli; M del C Cremona; R J Hirsig; P J Enriori
Journal:  Breast Cancer Res Treat       Date:  1992       Impact factor: 4.872

2.  Epidermal growth factor receptor assay: validation of a single point method and application to breast cancer.

Authors:  J L Formento; M Francoual; P Formento; M C Etienne; J L Fischel; M Namer; M Frenay; E François; G Milano
Journal:  Breast Cancer Res Treat       Date:  1991 Jan-Feb       Impact factor: 4.872

3.  Measurement of occupied and non-occupied epidermal growth factor receptor sites in 216 human breast cancer biopsies.

Authors:  N Falette; M F Lefebvre; F Meggouh; M Eynard; E Garin; S Saez
Journal:  Breast Cancer Res Treat       Date:  1992-03       Impact factor: 4.872

4.  Effects of vinorelbine on epidermal growth factor-receptor binding of human breast cancer cell lines in vitro.

Authors:  H Depenbrock; A Shirvani; J Rastetter; A R Hanauske
Journal:  Invest New Drugs       Date:  1995       Impact factor: 3.850

5.  Expression of epidermal growth factor receptor in benign and malignant primary tumours of the breast.

Authors:  P Möller; G Mechtersheimer; M Kaufmann; G Moldenhauer; F Momburg; T Mattfeldt; H F Otto
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

6.  EGF binding is quantitatively related to growth in node-positive breast cancer.

Authors:  E Spitzer; K Koepke; D Kunde; R Grosse
Journal:  Breast Cancer Res Treat       Date:  1988-09       Impact factor: 4.872

7.  Epidermal growth factor receptor overexpression and trisomy 7 in a case of Barrett's esophagus.

Authors:  H Garewal; P Meltzer; J Trent; R Prabhala; R Sampliner; M Korc
Journal:  Dig Dis Sci       Date:  1990-09       Impact factor: 3.199

8.  Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies.

Authors:  G D Lewis; I Figari; B Fendly; W L Wong; P Carter; C Gorman; H M Shepard
Journal:  Cancer Immunol Immunother       Date:  1993-09       Impact factor: 6.968

9.  Epidermal growth factor receptor in breast cancer: correlation of quantitative immunocytochemical assays to prognostic factors.

Authors:  C Charpin; B Devictor; P Bonnier; L Andrac; M N Lavaut; C Allasia; L Piana
Journal:  Breast Cancer Res Treat       Date:  1993       Impact factor: 4.872

10.  Growth factor expression in normal, benign, and malignant breast tissue.

Authors:  M T Travers; P J Barrett-Lee; U Berger; Y A Luqmani; J C Gazet; T J Powles; R C Coombes
Journal:  Br Med J (Clin Res Ed)       Date:  1988-06-11
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