Literature DB >> 6091323

Fluosol 43 particle localization pattern in target organs of rats. An electron microscopy study.

S Caiazza, C Fanizza, M Ferrari.   

Abstract

Perfluorocarbons (PFCs), chemically inert fluorinated organic compounds with high binding capacity for O2, are under discussion as substitutes for erythrocytes. Given the paucity of E.M. observations after their use, the aim of this study was to provide more extensive ultrastructural data about PFC particle size in the emulsion and about the localization pattern in organs of rats after infusion of Fluosol 43. Attention has been focused on the particle relationships with subcellular structures and on the subsequent histopathological implications.

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Year:  1984        PMID: 6091323     DOI: 10.1007/bf00704058

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN: 0174-7398


  22 in total

1.  Fluorocarbon emulsion as a candidate for artificial blood. Correlation between particle size of the emulsion and acute toxicity.

Authors:  T Fujita; T Sumaya; K Yokoyama
Journal:  Eur Surg Res       Date:  1971       Impact factor: 1.745

2.  Efficacy of a blood substitute (Fluosol-DA, 20%) on cerebral ischemia.

Authors:  Y Oda; H Handa; S Nagasawa; Y Naruo; R Asato; Y Yonekawa
Journal:  Neurol Res       Date:  1982       Impact factor: 2.448

3.  FDA committee questions Fluosol efficacy; US approval not imminent.

Authors:  C Marwick
Journal:  JAMA       Date:  1983-11-18       Impact factor: 56.272

4.  Studies on RES function in rats and mice after different doses of fluosol.

Authors:  J Lutz
Journal:  Prog Clin Biol Res       Date:  1983

5.  Further studies on intake and retention of PFC substance of Fluosol-DA in RES in humans.

Authors:  T Mitsuno; Y Tabuchi; H Ohyanagi; T Sugiyama
Journal:  Prog Clin Biol Res       Date:  1983

6.  Fluorocarbons: properties and syntheses.

Authors:  D D Dixon; D G Holland
Journal:  Fed Proc       Date:  1975-05

7.  Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure.

Authors:  L C Clark; F Gollan
Journal:  Science       Date:  1966-06-24       Impact factor: 47.728

8.  Activation of plasma complement by perfluorocarbon artificial blood: probable mechanism of adverse pulmonary reactions in treated patients and rationale for corticosteroids prophylaxis.

Authors:  G M Vercellotti; D E Hammerschmidt; P R Craddock; H S Jacob
Journal:  Blood       Date:  1982-06       Impact factor: 22.113

9.  Alterations of liver and spleen following intravenous infusion of fluorocarbon emulsions.

Authors:  W I Rosenblum; M G Hadfield; A J Martinez; P Schatzki
Journal:  Arch Pathol Lab Med       Date:  1976-04       Impact factor: 5.534

10.  Clinical studies of a perfluorochemical whole blood substitute (Fluosol-DA) Summary of 186 cases.

Authors:  T Mitsuno; H Ohyanagi; R Naito
Journal:  Ann Surg       Date:  1982-01       Impact factor: 12.969

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  1 in total

1.  Alteration of mitochondrial bioenergetics due to intravenous injection of a perfluorocarbon emulsion.

Authors:  D Branca; S M Chiarelli; E Vincenti; C Tortorella; G Scutari
Journal:  Experientia       Date:  1994-07-15
  1 in total

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