| Literature DB >> 6090474 |
D A Lawrence, R Pircher, C Krycève-Martinerie, P Jullien.
Abstract
Normal chicken, mouse, and human embryo fibroblasts release into their culture media transforming growth factors (TGFs) in a latent form. Their soft agar colony-forming activity on two widely used target cells, rat NRK-49F and mouse AKR-2B, is essentially revealed only after prior acidification of cell-conditioned media. These TGFs are EGF-dependent when assayed on NRK-49F cells and EGF-independent on AKR-2B cells. The TGF activity from the chicken source is released in three (apparent) molecular weight forms of 500 kd, 125 kd, and 20 kd.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6090474 DOI： 10.1002/jcp.1041210123
Source DB: PubMed Journal: J Cell Physiol ISSN： 0021-9541 Impact factor: 6.384