Literature DB >> 11462045

Viral load increases in SJL/J mice persistently infected by Theiler's virus after inactivation of the beta(2)m gene.

S Aubagnac1, M Brahic, J F Bureau.   

Abstract

We show that inactivating the beta(2)m gene increases the viral load of SJL/J mice persistently infected by Theiler's virus. Together with previous results, this shows that the characteristics of Tmevp1, a locus which controls the amount of viral RNA that persists in the central nervous system, are those of an H-2 class I gene.

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Year:  2001        PMID： 11462045      PMCID： PMC115008          DOI： 10.1128/JVI.75.16.7723-7726.2001

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  Roles of the H-2D(b) and H-K(b) genes in resistance to persistent Theiler's murine encephalomyelitis virus infection of the central nervous system.

Authors:  Arièle Azoulay-Cayla; Sylvie Syan; Michel Brahic; Jean-François Bureau
Journal:  J Gen Virol       Date:  2001-05       Impact factor: 3.891

2.  Two loci, Tmevp2 and Tmevp3, located on the telomeric region of chromosome 10, control the persistence of Theiler's virus in the central nervous system of mice.

Authors:  F Bihl; M Brahic; J F Bureau
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

3.  Mutation of a major histocompatibility class I locus, H-2D, leads to an increased virus burden and disease susceptibility in Theiler's virus-induced demyelinating disease.

Authors:  H L Lipton; R Melvold; S D Miller; M C Dal Canto
Journal:  J Neurovirol       Date:  1995-06       Impact factor: 2.643

4.  H-2 Dd transgene suppresses Theiler's virus-induced demyelination in susceptible strains of mice.

Authors:  M Rodriguez; C S David
Journal:  J Neurovirol       Date:  1995-03       Impact factor: 2.643

5.  Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination.

Authors:  H L Lipton
Journal:  Infect Immun       Date:  1975-05       Impact factor: 3.441

6.  H-2D(b-/-) mice are susceptible to persistent infection by Theiler's virus.

Authors:  A Azoulay-Cayla; S Dethlefs; B Pérarnau; E L Larsson-Sciard; F A Lemonnier; M Brahic; J F Bureau
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

7.  New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice.

Authors:  R J Butterfield; J D Sudweeks; E P Blankenhorn; R Korngold; J C Marini; J A Todd; R J Roper; C Teuscher
Journal:  J Immunol       Date:  1998-08-15       Impact factor: 5.422

Review 8.  Genetics of susceptibility to Theiler's virus infection.

Authors:  M Brahic; J F Bureau
Journal:  Bioessays       Date:  1998-08       Impact factor: 4.345

Review 9.  The infection of mouse by Theiler's virus: from genetics to immunology.

Authors:  P Monteyne; J F Bureau; M Brahic
Journal:  Immunol Rev       Date:  1997-10       Impact factor: 12.988

10.  Viral load and a locus on chromosome 11 affect the late clinical disease caused by Theiler's virus.

Authors:  S Aubagnac; M Brahic; J F Bureau
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103
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  5 in total

1.  Bone marrow chimeras reveal non-H-2 hematopoietic control of susceptibility to Theiler's virus persistent infection.

Authors:  Stéphanie Aubagnac; Michel Brahic; Jean-François Bureau
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

2.  Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease.

Authors:  Mark Trottier; Brian P Schlitt; Aisha Y Kung; Howard L Lipton
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

3.  Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon.

Authors:  Soline Vigneau; Pierre-Simon Rohrlich; Michel Brahic; Jean-François Bureau
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

4.  Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases.

Authors:  F Levillayer; M Mas; F Levi-Acobas; M Brahic; J F Bureau
Journal:  Genetics       Date:  2007-05-04       Impact factor: 4.562

Review 5.  Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosis.

Authors:  Ikuo Tsunoda; Robert S Fujinami
Journal:  J Neuroimmune Pharmacol       Date:  2009-11-06       Impact factor: 4.147
  5 in total

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