Literature DB >> 6086815

Early virion-associated suppression of cellular protein synthesis by herpes simplex virus is accompanied by inactivation of mRNA.

M L Fenwick, M M McMenamin.   

Abstract

Vero cells infected with herpes simplex virus in the presence of actinomycin or cycloheximide, or with u.v.-inactivated virus, suffered a rapid loss of functional mRNA as determined by translation in vitro. It is suggested that a virion-associated factor causes a structural change in the mRNA of the host cell.

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Year:  1984        PMID： 6086815     DOI： 10.1099/0022-1317-65-7-1225

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  55 in total

1.  Picornavirus internal ribosome entry site elements target RNA cleavage events induced by the herpes simplex virus virion host shutoff protein.

Authors:  M M Elgadi; J R Smiley
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

2.  The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

Authors:  Christopher R Cotter; Won-keun Kim; Marie L Nguyen; Jacob S Yount; Carolina B López; John A Blaho; Thomas M Moran
Journal:  J Virol       Date:  2011-09-21       Impact factor: 5.103

3.  mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.

Authors:  David N Everly; Pinghui Feng; I Saira Mian; G Sullivan Read
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

Review 4.  Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?

Authors:  James R Smiley
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

5.  The virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.

Authors:  Heidi G Page; G Sullivan Read
Journal:  J Virol       Date:  2010-04-28       Impact factor: 5.103

6.  mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.

Authors:  Pinghui Feng; David N Everly; G Sullivan Read
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

7.  Human topoisomerase 1 messenger RNA is not destabilized by the herpes simplex virus type 2 virion-associated shut-off function.

Authors:  K F Bastow; B S Zhou; Y C Cheng
Journal:  Virus Genes       Date:  1989-08       Impact factor: 2.332

8.  Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.

Authors:  L I Strelow; D A Leib
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Induction of interleukin-8 gene expression is associated with herpes simplex virus infection of human corneal keratocytes but not human corneal epithelial cells.

Authors:  J E Oakes; C A Monteiro; C L Cubitt; R N Lausch
Journal:  J Virol       Date:  1993-08       Impact factor: 5.103

10.  The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.

Authors:  M A Hardwicke; R M Sandri-Goldin
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103
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