Linear analogue self-assessment of voice quality in laryngeal cancer.

This study evaluated the reliability and sensitivity of laryngeal cancer patients' linear analogue self-assessments (LASA) of voice quality. Thirty patients completed LASA scales for a number of voice-related symptoms and abilities several times during a standard treatment programme. The study design allowed evaluation of the scales' reliability, both early and late in treatment, and sensitivity to the changes expected during irradiation. Another 29 post-treatment patients completed the same scales in interviews separated by several weeks. Results indicate that LASA scores were generally reliable, sensitive to clinical change, yet stable when clinical status is unaltered. Though further demonstrations of the validity of these scales are required, their possible use as outcome measures in future clinical trials comparing treatments for laryngeal cancer is feasible.