Literature DB >> 6067566

Addiction liability of albino rats: breeding for quantitive differences in morphine drinking.

J R Nichols, S Hsiao.   

Abstract

Selective breeding produced two strains of rats that differ in their susceptibility to morphine addiction. Inbreeding the more susceptible rats in an unselected population produced susceptible offspring; inbreeding resistant rats produced resistant offspring. Further selection and inbreeding increased the strain difference in the F(2) and F(3) generations. The F(3) generation also differed in their susceptibility to alcohol addiction.

Entities:  

Mesh：

Year:  1967        PMID： 6067566     DOI： 10.1126/science.157.3788.561

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  The effect of housing and gender on morphine self-administration in rats.

Authors:  B K Alexander; R B Coambs; P F Hadaway
Journal:  Psychopharmacology (Berl)       Date:  1978-07-06       Impact factor: 4.530

2.  Morphine suppression of ethanol withdrawal in mice.

Authors:  K Blum; J E Wallace; H A Schwerter; J D Eubanks
Journal:  Experientia       Date:  1976-01-15

3.  Genotype-dependent sensitivity and tolerance to morphine and heroin: dissociation between opiate-induced running and analgesia in the mouse.

Authors:  A Oliverio; C Castellano
Journal:  Psychopharmacologia       Date:  1974

4.  Morphine adaptation, hexobarbital, alcoholism. General remarks.

Authors:  W Kalow
Journal:  Humangenetik       Date:  1970

5.  Selective breeding for high and low levels of opiate-induced analgesia in mice.

Authors:  J K Belknap; N R Haltli; D M Goebel; M Lamé
Journal:  Behav Genet       Date:  1983-07       Impact factor: 2.805

6.  Opioid peptides as neuroregulators: potential areas for the study of genetic-behavioral mechanisms.

Authors:  J D Barchas; S Sullivan
Journal:  Behav Genet       Date:  1982-02       Impact factor: 2.805

7.  Oral etonitazene and cocaine consumption by AA, ANA and Wistar rats.

Authors:  P Hyyatiä; J D Sinclair
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

8.  Differences in morphine reinforcement property in two inbred rat strains: associations with cortical receptors, behavioral activity, analgesia and the cataleptic effects of morphine.

Authors:  S K Sudakov; S R Goldberg; E V Borisova; L A Surkova; I V Turina; G I Elmer
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

9.  Intravenous morphine self-administration by rats with low versus high saccharin preferences.

Authors:  B A Gosnell; K E Lane; S M Bell; D D Krahn
Journal:  Psychopharmacology (Berl)       Date:  1995-01       Impact factor: 4.530

10.  Contributions of taste factors and gender to opioid preference in C57BL and DBA mice.

Authors:  M L Forgie; B L Beyerstein; B K Alexander
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530
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