Literature DB >> 606257

Effect of Methylene Blue on glutamate and reduced glutathione of rabbit erythrocytes.

J E Smith, E Mahaffey, M Lee.   

Abstract

Methylene Blue injected into rabbits resulted in increased glutamate, reduced glutathione and pyrrolid-2-one-5-carboxylate in erythrocytes. The increase in reduced glutathione was probably due to increased glutamate changing the feedback control of glutathione on gamma-glutamylcysteine synthetase.

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Year:  1977        PMID： 606257      PMCID： PMC1183811          DOI： 10.1042/bj1680587

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  14 in total

1.  UTILIZATION OF ALPHA-KETOGLUTARATE BY RED BLOOD CELLS FOR GLUTATHIONE SYNTHESIS.

Authors:  M D SASS
Journal:  Nature       Date:  1963-12-21       Impact factor: 49.962

2.  DETERMINATION OF CYSTEINE.

Authors:  S ROSTON
Journal:  Anal Biochem       Date:  1963-12       Impact factor: 3.365

3.  Pyroglutamic aciduria. Studies in an infant with chronic metabolic acidosis.

Authors:  L Hagenfeldt; A Larsson; R Zetterström
Journal:  Acta Paediatr Scand       Date:  1974-01

4.  Relationship of in vivo erythrocyte glutathione flux to the oxidized glutathione transport system.

Authors:  J E Smith
Journal:  J Lab Clin Med       Date:  1974-03

5.  The effect of methylene blue and diaminodiphenysulfone on red cell reduced glutathione synthesis.

Authors:  N V Paniker; E Beutler
Journal:  J Lab Clin Med       Date:  1972-10

6.  [The biosynthesis of glutathione in human erythrocytes (author's transl)].

Authors:  H Heinle; G Sawatzki; A Wendel
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1976-11

7.  Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione.

Authors:  P G Richman; A Meister
Journal:  J Biol Chem       Date:  1975-02-25       Impact factor: 5.157

8.  Formation of 5-oxoproline from glutathione in erythrocytes by the gamma-glutamyltranspeptidase-cyclotransferase pathway.

Authors:  A G Palekar; S S Tate; A Meister
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205

9.  Glutathione synthetase deficiency, an inborn error of metabolism involving the gamma-glutamyl cycle in patients with 5-oxoprolinuria (pyroglutamic aciduria).

Authors:  V P Wellner; R Sekura; A Meister; A Larsson
Journal:  Proc Natl Acad Sci U S A       Date:  1974-06       Impact factor: 11.205

10.  Studies in the enzymology of glutathione metabolism in human erythrocytes.

Authors:  R C Jackson
Journal:  Biochem J       Date:  1969-02       Impact factor: 3.857
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