Literature DB >> 6058689

Pemoline levels in brain: enhancement by dimethyl sulfoxide.

J J Brink, D G Stein.   

Abstract

Pemoline-C(14) dissolved in dimethyl sulfoxide and injected intraperitoneally into rats was found in larger amounts in the brain than was a similar dose given in 0.3 percent tragacanth suspension. This appeared to be related to a partial breakdown of the blood-brain barrier in vivo by the dimethyl sulfoxide.

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Year:  1967        PMID： 6058689     DOI： 10.1126/science.158.3807.1479

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  Magnesium pemoline: effects of a broad range of doses on water maze performance.

Authors:  J E McCarroll; S F Korbel
Journal:  Psychopharmacologia       Date:  1972

2.  Influence of ouabain, DNP and DMSO on amino-acid transfer out of the subarachnoid space.

Authors:  P M Wright; I H Main
Journal:  Br J Pharmacol       Date:  1971-10       Impact factor: 8.739

3.  Acute intraperitoneal toxicity of DDT and PCB's in mice using two solvents.

Authors:  V Lewin; W A McBlain; F H Wolfe
Journal:  Bull Environ Contam Toxicol       Date:  1972-10       Impact factor: 2.151

4.  Little effect of dimethyl sulfoxide on blood-brain barrier to dopamine.

Authors:  A Walters; V Jackson-Lewis; S Fahn
Journal:  Experientia       Date:  1984-08-15

5.  Enhancement of ketoconazole penetration across the blood-brain barrier of mice by dimethyl sulfoxide.

Authors:  P C Iwen; N G Miller
Journal:  Antimicrob Agents Chemother       Date:  1986-10       Impact factor: 5.191

6.  Local penetration of gentamicin into the femoral cortex of rats.

Authors:  Y Mirovsky; N Halperin; L Copeliovitch
Journal:  Arch Orthop Trauma Surg       Date:  1984

7.  [The effect of dimethyl sulfoxide (DMSO) on human skin cultures. Morphological and autoradiographic studies].

Authors:  K H Korfsmeier
Journal:  Arch Klin Exp Dermatol       Date:  1969

8.  Factors restricting maximal preservation of neuronal glycogen after perfusion fixation with dimethyl sulfoxide and iodoacetic acid in Bouin's solution. Histochemical observations in the brain of the Netherlands dwarf rabbit.

Authors:  J Cammermeyer; I M Fenton
Journal:  Histochemistry       Date:  1982

9.  Regulation of motivation for food by neuromedin U in the paraventricular nucleus and the dorsal raphe nucleus.

Authors:  D L McCue; J M Kasper; J D Hommel
Journal:  Int J Obes (Lond)       Date:  2016-10-17       Impact factor: 5.095
  9 in total

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