Literature DB >> 6057798

Serological comparison of spherules and arthrospores of Coccidioides immitis.

M E Landay, R W Wheat, N F Conant, E P Lowe.   

Abstract

Spherule and arthrospore cellular preparations were sonic-treated and separated into their respective supernatant and sediment components. Complement-fixation tests with antispherule and antiarthrospore pooled rabbit sera revealed that the soluble antigens exhibited more serological activity than the sediment preparations. After autoclaving, an arthrospore cellular antigen exhibited increased activity with either antisera, whereas autoclaved spherules exhibited increased activity only with antispherule serum. Complement-fixation tests with coccicioidin and spherule culture supernatant preparations revealed quantitative or qualitative differences in antigenic determinants between these two morphological phases of Coccidioides immitis.

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Year:  1967        PMID： 6057798      PMCID： PMC276838          DOI： 10.1128/jb.94.5.1400-1405.1967

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  15 in total

1.  IMMUNIZATION AGAINST EXPERIMENTAL LETHAL SIMIAN COCCIDIOIDOMYCOSIS USING WHOLE KILLED ARTHROSPORES AND CELL FRACTION.

Authors:  J T SINSKI; E P LOWE; N F CONANT; H F HARDIN; M W CASTLEBERRY; J G RAY
Journal:  Mycologia       Date:  1965 May-Jun       Impact factor: 2.696

2.  Immunogenic properties of nondisrupted and disrupted spherules of Coccidioides immitis in mice.

Authors:  Y C KONG; H B LEVINE; C E SMITH
Journal:  Sabouraudia       Date:  1963-02

3.  Rapid production of complement fixation antigens for systemic mycotic diseases. I. Coccidioidin: influence of media and mechanical agitation on its development.

Authors:  L AJELLO; K WALLS; J C MOORE; R FALCONE
Journal:  J Bacteriol       Date:  1959-06       Impact factor: 3.490

4.  Purification of the spherule-endospore phase of Coccidioides immitis.

Authors:  H B LEVINE
Journal:  Sabouraudia       Date:  1961-06

5.  Immunity to coccidioi-domycosis induced in mice by purified spherule, arthrospore, and mycelial vaccines.

Authors:  H B LEVINE; J M COBB; C E SMITH
Journal:  Trans N Y Acad Sci       Date:  1960-04

6.  Effect of surface active agents on endosporulation of Coccidioides immitis in a chemically defined medium.

Authors:  J L CONVERSE
Journal:  J Bacteriol       Date:  1957-07       Impact factor: 3.490

7.  Serological tests in the diagnosis and prognosis of coccidioidomycosis.

Authors:  C E SMITH; M T SAITO; R R BEARD; R M KEPP; R W CLARK; B U EDDIE
Journal:  Am J Hyg       Date:  1950-07

8.  Serological comparison of the three morphological phases of Coccidioides immitis by the agar gel diffusion method.

Authors:  M E Landay; R W Wheat; N F Conant; E P Lowe
Journal:  J Bacteriol       Date:  1967-01       Impact factor: 3.490

Review 9.  Experimentally induced immunity in the mycoses.

Authors:  Y C Kong; H B Levine
Journal:  Bacteriol Rev       Date:  1967-03

10.  COMPLEMENT-FIXATION TITERS IN EXPERIMENTAL COCCIDIOIDOMYCOSIS IN RABBITS.

Authors:  E A BROSBE; J N KIETZMAN; N B KURNICK
Journal:  J Bacteriol       Date:  1964-07       Impact factor: 3.490
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  4 in total

1.  Soluble antigens of mycelia and spherules in the in vitro detection of immunity to Coccidioides immitis.

Authors:  S C Deresinski; H B Levine; D A Stevens
Journal:  Infect Immun       Date:  1974-10       Impact factor: 3.441

Review 2.  Biochemical challenge of microbial pathogenicity.

Authors:  H Smith
Journal:  Bacteriol Rev       Date:  1968-09

3.  Development of vaccines for coccidioidomycosis.

Authors:  H B Levine; D Pappagianis; J M Cobb
Journal:  Mycopathol Mycol Appl       Date:  1970

4.  Delayed-type hypersensitivity responses to a cell wall fraction of the mycelial phase of Coccidioides immitis.

Authors:  E R Ward; R A Cox; J A Schmitt; M Huppert; S H Sun
Journal:  Infect Immun       Date:  1975-11       Impact factor: 3.441
  4 in total

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