Literature DB >> 6049858

The effects of diethylstilboestrol and castration on the nucleic acid and protein metabolism of rat prostate gland.

F R Mangan, G E Neal, D C Williams.   

Abstract

1. Implantation of diethylstilboestrol pellets into adult male rats brings about similar biochemical changes in the nucleic acid and protein metabolism to castration. 2. The avidity of the prostate for labelled diethylstilboestrol was greater than that of the other organs examined. 3. Uptake of labelled diethylstilboestrol and testosterone into the nuclei of the rat prostate is greater in castrated rats than in controls. 4. Diethylstilboestrol appeared to be associated with the protein and not with the DNA fraction of the nucleus.

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Year:  1967        PMID： 6049858      PMCID： PMC1271254          DOI： 10.1042/bj1041075

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  24 in total

1.  GROWTH PATTERN OF THE MOUSE PROSTATE GLAND IN ORGAN CULTURE AND ITS RESPONSE TO SEX HORMONES, VITAMIN A, AND 3-METHYLCHOLANTHRENE.

Authors:  I LASNITZKI
Journal:  Natl Cancer Inst Monogr       Date:  1963-10

2.  DENSITY GRADIENT CENTRIFUGATION IN ANGLE-HEAD ROTORS.

Authors:  W D FISHER; G B CLINE; N G ANDERSON
Journal:  Anal Biochem       Date:  1964-12       Impact factor: 3.365

3.  DETERMINATION OF THE CODING RATIO BASED ON MOLECULAR WEIGHT OF MESSENGER RIBONUCLEIC ACID ASSOCIATED WITH ERGOSOMES OF DIFFERENT AGGREGATE SIZE.

Authors:  T STAEHELIN; F O WETTSTEIN; H OURA; H NOLL
Journal:  Nature       Date:  1964-01-18       Impact factor: 49.962

4.  Ribosomal aggregate engaged in protein synthesis: characterization of the ergosome.

Authors:  F O WETTSTEIN; T STAEHELIN; H NOLL
Journal:  Nature       Date:  1963-02-02       Impact factor: 49.962

5.  An effect of testosterone on amino acid incorporation by prostatic ribonucleoprotein particles.

Authors:  S LIAO; H G WILLIAMS-ASHMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1962-11-15       Impact factor: 11.205

6.  Estrogen inhibition of androgen-maintained prostatic secretion in the hypophysectomized dog.

Authors:  D A GOODWIN; D S RASMUSSEN-TAXDAL; A A FERREIRA; W W SCOTT
Journal:  J Urol       Date:  1961-07       Impact factor: 7.450

7.  A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.

Authors:  K BURTON
Journal:  Biochem J       Date:  1956-02       Impact factor: 3.857

8.  A procedure for the isolation of enzymically active rat-liver nuclei.

Authors:  C C Widnell; J R Tata
Journal:  Biochem J       Date:  1964-08       Impact factor: 3.857

9.  Rapid effect of testosterone on ribonucleic acid polymerase activity of rat ventral prostate.

Authors:  S Liao; K R Leininger; D Sagher; R W Barton
Journal:  Endocrinology       Date:  1965-10       Impact factor: 4.736

10.  2-Acetamidofluorene and 3-methylcholanthrene: differences in binding to rat liver deoxyribonucleic acid in vivo.

Authors:  M B Sporn; C W Dingman
Journal:  Nature       Date:  1966-04-30       Impact factor: 49.962
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  9 in total

1.  Signaling through estrogen receptors modulates telomerase activity in human prostate cancer.

Authors:  Simona Nanni; Michela Narducci; Linda Della Pietra; Fabiola Moretti; Annalisa Grasselli; Piero De Carli; Ada Sacchi; Alfredo Pontecorvi; Antonella Farsetti
Journal:  J Clin Invest       Date:  2002-07       Impact factor: 14.808

2.  Further studies on the stimulation of protein synthesis in androgen-dependent tissues by testosterone.

Authors:  W I Mainwaring; P A Wilce
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

3.  Hormonal effects in vitro on prostatic ribonucleic acid polymerase.

Authors:  P Davies; A R Fahmy; C G Pierrepoint; K Griffiths
Journal:  Biochem J       Date:  1972-10       Impact factor: 3.857

4.  The control of the form and function of the ribosomes in androgen-dependent tissues by testosterone.

Authors:  W I Mainwaring; P A Wilce
Journal:  Biochem J       Date:  1973-07       Impact factor: 3.857

5.  Androgen-dependent synthesis of basic secretory proteins by the rat seminal vesicle.

Authors:  S J Higgins; J M Burchell; W I Mainwaring
Journal:  Biochem J       Date:  1976-08-15       Impact factor: 3.857

6.  Changes in the ribonucleic acid metabolism of aging mouse tissues with particular reference to the prostate gland.

Authors:  W I Mainwaring
Journal:  Biochem J       Date:  1968-11       Impact factor: 3.857

7.  Studies on steroid fever. II. Pyrogenic and anti-pyrogenic activity in vitro of some endogenous steroids of man.

Authors:  G M Dillard; P Bodel
Journal:  J Clin Invest       Date:  1970-12       Impact factor: 14.808

8.  The inhibition of deoxyribonucleic acid nucleotidyltransferase by stilboestrol derivatives.

Authors:  A R Fahmy; K Griffiths
Journal:  Biochem J       Date:  1968-08       Impact factor: 3.857

9.  Relationship of oestrogen receptor alpha gene polymorphisms with risk for benign prostatic hyperplasia and prostate cancer in Chinese men.

Authors:  Zihua Han; Lingzhi Zhang; Rujian Zhu; Lifei Luo; Min Zhu; Lilong Fan; Guanfu Wang
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889
  9 in total

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