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Literature DB >> 60471

Lipid composition of myelin in multiple sclerosis.

Abstract

Myelin was isolated from histologically normal white matter and plaques from MS patients and from white matter of neurologically normal controls. No difference was found in the total lipid content. There were no detectable deficits in MS myelin of phosphoglycerides, plasmalogens or sphingolipids. Gangliosides and lysolecithin were not detected. Analysis of the fatty aldehyde composition of the phosphoglycerides and the fatty acid composition of the cholesteryl esters, phosphoglycerides and sphingolipids did not show any differences between the normal and MS myelin.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1976 PMID： 60471 DOI： 10.1007/bf00313273

Source DB: PubMed Journal: J Neurol ISSN： 0340-5354 Impact factor: 4.849

30 in total

1. Lipid chemistry of the brain in demyelinating diseases.

Authors: J N CUMINGS
Journal: Brain Date: 1955 Impact factor: 13.501

2. Multiple sclerosis.

Authors: L C SCHEINBERG; S R KOREY
Journal: Annu Rev Med Date: 1962 Impact factor: 13.739

3. Myelin constituents of human central nervous system.

Authors: J Clausen; I B Hansen
Journal: Acta Neurol Scand Date: 1970 Impact factor: 3.209

4. Lipids and proteins in multiple sclerosis white matter.

Authors: B Gerstl; L F Eng; M Tavaststjerna; J K Smith; S L Kruse
Journal: J Neurochem Date: 1970-05 Impact factor: 5.372

5. Cholesterol esters in myelin isolated from cerebral white matter of patients with multiple sclerosis.

Authors: M E Fewster; J F Mead; F J Wolfgram; W W Tourtellotte
Journal: Proc Soc Exp Biol Med Date: 1970-03

6. On the composition of human myelin.

Authors: B Gerstl; L F Eng; R B Hayman; M G Tavaststjerna; P R Bond
Journal: J Neurochem Date: 1967-06 Impact factor: 5.372

7. Lipid composition of the normal human brain: gray matter, white matter, and myelin.

Authors: J S O'Brien; E L Sampson
Journal: J Lipid Res Date: 1965-10 Impact factor: 5.922

8. Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin.

Authors: J S O'Brien; E L Sampson
Journal: J Lipid Res Date: 1965-10 Impact factor: 5.922

9. Allergic encephalomyelitis induced by brain antigen after deficiency in polyunsaturated fatty acids during myelination. Is multiple sclerosis a nutritive disorder?

Authors: J Clausen; J Moller
Journal: Acta Neurol Scand Date: 1967 Impact factor: 3.209

10. The encephalomyelitic activity of myelin isolated by ultracentrifugation.

Authors: R H LAATSCH; M W KIES; S GORDON; E C ALVORD
Journal: J Exp Med Date: 1962-04-01 Impact factor: 14.307

10 in total

Review 1. Magnetic resonance imaging of myelin.

Authors: Cornelia Laule; Irene M Vavasour; Shannon H Kolind; David K B Li; Tony L Traboulsee; G R Wayne Moore; Alex L MacKay
Journal: Neurotherapeutics Date: 2007-07 Impact factor: 7.620

Review 2. Is the myelin membrane abnormal in multiple sclerosis?

Authors: D D Wood; M A Moscarello
Journal: J Membr Biol Date: 1984 Impact factor: 1.843

3. The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis.

Authors: Maria Podbielska; Steven B Levery; Edward L Hogan
Journal: Clin Lipidol Date: 2011-04

Lipid composition of myelin in multiple sclerosis.

1. Lipid chemistry of the brain in demyelinating diseases.

2. Multiple sclerosis.

3. Myelin constituents of human central nervous system.

4. Lipids and proteins in multiple sclerosis white matter.

5. Cholesterol esters in myelin isolated from cerebral white matter of patients with multiple sclerosis.

6. On the composition of human myelin.

7. Lipid composition of the normal human brain: gray matter, white matter, and myelin.

8. Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin.

9. Allergic encephalomyelitis induced by brain antigen after deficiency in polyunsaturated fatty acids during myelination. Is multiple sclerosis a nutritive disorder?

10. The encephalomyelitic activity of myelin isolated by ultracentrifugation.

Review 1. Magnetic resonance imaging of myelin.

Review 2. Is the myelin membrane abnormal in multiple sclerosis?

3. The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis.

4. Fatty acid and sterol specificity of cholesterol esterifying enzyme in developing rat brain.

5. Comparison of two molecular species of ethanolamine plasmalogen in multiple sclerosis and normal myelin.

6. A comparison of composition and fluidity of multiple sclerosis and normal myelin.

7. Comprehensive Analysis of Age-related Changes in Lipid Metabolism and Myelin Sheath Formation in Sciatic Nerves.

8. Cholesterol and Cardiolipin Importance in Local Anesthetics-Membrane Interactions: The Langmuir Monolayer Study.

9. Myelin recovery in multiple sclerosis: the challenge of remyelination.

Review 10. Magnetic Resonance of Myelin Water: An in vivo Marker for Myelin.