Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Citrate content of liver and kidney of rat in various metabolic states and in fluoroacetate poisoning.

Literature DB >> 6032977

Citrate content of liver and kidney of rat in various metabolic states and in fluoroacetate poisoning.

Abstract

The citrate content of rat liver changes little when normal rats are starved, when starved rats are re-fed with various diets and when normal animals are made diabetic with alloxan. The citrate content of rat kidney changes little on starvation, but it doubles on induction of diabetes. Fluoroacetate poisoning has relatively little effect on the citrate content of liver under a variety of conditions except that normal female rats show a 2.4-fold increase. Fluoroacetate poisoning leads to increases in the citrate content of kidney under all conditions. The relevance of these observations to the regulation of fatty acid synthesis is discussed. The acetic anhydride-pyridine method and the pentabromoacetone method for the estimation of citrate are compared.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1967 PMID： 6032977 PMCID： PMC1270414 DOI： 10.1042/bj1030342

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

35 in total

1. THE CONVERSION OF GLUTAMATE CARBON TO FATTY ACID CARBON VIA CITRATE. I. THE INFLUENCE OF GLUCOSE IN LACTATING RAT MAMMARY GLAND SLICES.

Authors: J MADSEN; S ABRAHAM; I L CHAIKOFF
Journal: J Biol Chem Date: 1964-05 Impact factor: 5.157

2. Lipid metabolism.

Authors: S J WAKIL
Journal: Annu Rev Biochem Date: 1962 Impact factor: 23.643

3. Factors influencing the rates of long-chain fatty acid oxidation and synthesis in mammalian systems.

Authors: I B FRITZ
Journal: Physiol Rev Date: 1961-01 Impact factor: 37.312

4. Fluoroacetyl coenzyme A.

Authors: R O BRADY
Journal: J Biol Chem Date: 1955-11 Impact factor: 5.157

5. Some effects of synthetic fluoro compounds on the metabolism of acetate and citrate.

Authors: E M GAL; R A PETERS; R W WAKELIN
Journal: Biochem J Date: 1956-09 Impact factor: 3.857

6. Levels of acids of the citric acid cycle in tissues of normal and diabetic rats.

Authors: C E FROHMAN; J M ORTEN; A H SMITH
Journal: J Biol Chem Date: 1951-12 Impact factor: 5.157

Review 7. The cellular control of fatty acid synthesis at the enzymatic level.

Authors: F Lynen; M Matsuhashi; S Numa; E Schweizer
Journal: Biochem Soc Symp Date: 1963

8. The effect of glycerol 3-phosphate on fatty acid synthesis.

Authors: C F Howard; J M Lowenstein
Journal: J Biol Chem Date: 1965-11 Impact factor: 5.157

9. Regulation of glucose uptake by muscles. 10. Effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glycerol output and concentrations of free fatty acids, long-chain fatty acyl-coenzyme A, glycerol phosphate and citrate-cycle intermediates in rat heart and diaphragm muscles.

Authors: P B Garland; P J Randle
Journal: Biochem J Date: 1964-12 Impact factor: 3.857

9. Light and electron microscopic studies of the rat kidney after administration of inhibitors of the citric acid cycle in vivo. I. Effects of sodium fluoroacetate on the proximal convoluted tubule.

Authors: E M McDowell
Journal: Am J Pathol Date: 1972-03 Impact factor: 4.307

10. Hormonal regulation of adipose-tissue acetyl-Coenzyme A carboxylase by changes in the polymeric state of the enzyme. The role of long-chain fatty acyl-Coenzyme A thioesters and citrate.

Authors: A P Halestrap; R M Denton
Journal: Biochem J Date: 1974-08 Impact factor: 3.857

Citrate content of liver and kidney of rat in various metabolic states and in fluoroacetate poisoning.

1. THE CONVERSION OF GLUTAMATE CARBON TO FATTY ACID CARBON VIA CITRATE. I. THE INFLUENCE OF GLUCOSE IN LACTATING RAT MAMMARY GLAND SLICES.

2. Lipid metabolism.

3. Factors influencing the rates of long-chain fatty acid oxidation and synthesis in mammalian systems.

4. Fluoroacetyl coenzyme A.

5. Some effects of synthetic fluoro compounds on the metabolism of acetate and citrate.

6. Levels of acids of the citric acid cycle in tissues of normal and diabetic rats.

Review 7. The cellular control of fatty acid synthesis at the enzymatic level.

8. The effect of glycerol 3-phosphate on fatty acid synthesis.

10. Energy-linked incorporation of citrate into rat liver mitochondria.

1. Effects of starvation and alloxan diabetes on the content of citrate in the livers of the rat.

2. The influence of carbon dioxide on morphogenesis in Penicillium isariiforme.

3. Induction of fatty acid synthetase and acetyl-CoA carboxylase by isolated rat liver cells.

4. Regulation of acetyl-coA carboxylase: properties of coA activation of acetyl-coA carboxylase.

5. Sudden substrate dilution induces a higher rate of citric acid production by Aspergillus niger.

Review 6. Control of acetyl-CoA carboxylase by covalent modification.

7. Selectivity of protein oxidative damage during aging in Drosophila melanogaster.

8. Lipogenic enzyme activities in primary cultures of adult mouse hepatocytes.

9. Light and electron microscopic studies of the rat kidney after administration of inhibitors of the citric acid cycle in vivo. I. Effects of sodium fluoroacetate on the proximal convoluted tubule.

10. Hormonal regulation of adipose-tissue acetyl-Coenzyme A carboxylase by changes in the polymeric state of the enzyme. The role of long-chain fatty acyl-Coenzyme A thioesters and citrate.