Literature DB >> 6026668

Benzpyrene hydroxylase induction by polycyclic hydrocarbons in hamster embryonic cells grown in vitro.

L J Alfred, H V Gelboin.   

Abstract

Treatment of hamster embryonic cells with 1,2-benzanthracene for 4 to 48 hours induced a three- to tenfold increase in the activity of benzpyrene hydroxylase. That the increase in enzyme activity was completely prevented by puromycin suggested an induction of enzyme synthesis.

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Year:  1967        PMID： 6026668     DOI： 10.1126/science.157.3784.75

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Metabolism of polycyclic aromatic hydrocarbons in cultured human leukocytes under genetic control.

Authors:  G Kellermann; M Luyten-Kellermann; C R Shaw
Journal:  Humangenetik       Date:  1973-12-10

2.  Microspectrofluorometric study of benzo(a)pyrene metabolization in benzo(a)pyrene-grown single living cells.

Authors:  J M Salmon; E Kohen; C Kohen; G Bengtsson
Journal:  Histochemistry       Date:  1974

3.  A microspectrofluorometric approach for the study of benzo(a)pyrene and dibenzo(a, h)anthracene metabolization in single living cells.

Authors:  J M Salmon; E Kohen; C Kohen; G Bengtsson
Journal:  Histochemistry       Date:  1974

4.  Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs.

Authors:  D P Jackson; A D Joshi; C J Elferink
Journal:  Toxicol Res (Camb)       Date:  2015-03-17       Impact factor: 3.524

5.  Aryl hydrocarbon hydroxylase and polycyclic hydrocarbon tumorigenesis: effect of the enzyme inhibitor 7,8-benzoflavone on tumorigenesis and macromolecule binding.

Authors:  N Kinoshita; H V Gelboin
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205

6.  Enzymatic hydroxylation of benzopyrene and its relationship to cytotoxicity.

Authors:  H V Gelboin; E Huberman; L Sachs
Journal:  Proc Natl Acad Sci U S A       Date:  1969-12       Impact factor: 11.205
  6 in total

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