Literature DB >> 26783425

Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs.

D P Jackson, A D Joshi, C J Elferink.   

Abstract

The Ah receptor is a transcription factor that modulates gene expression via interactions with multiple protein partners; these are reviewed, including the novel NC-XRE pathway involving KLF6.

Entities:  

Year:  2015        PMID： 26783425      PMCID： PMC4714567          DOI： 10.1039/c4tx00236a

Source DB:  PubMed          Journal:  Toxicol Res (Camb)        ISSN： 2045-452X            Impact factor:   3.524


  253 in total

1.  The genetics of aryl hydrocarbon hydroxylase induction in mice: a single gene difference between C57BL-6J and DBA-2J.

Authors:  P E Thomas; R E Kouri; J J Hutton
Journal:  Biochem Genet       Date:  1972-04       Impact factor: 1.890

2.  Downregulation of aryl hydrocarbon receptor function and cytochrome P450 1A1 induction by expression of Ha-ras oncogenes.

Authors:  J J Reiners; C L Jones; N Hong; R E Clift; C Elferink
Journal:  Mol Carcinog       Date:  1997-06       Impact factor: 4.784

3.  Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

Authors:  A B Okey; G P Bondy; M E Mason; G F Kahl; H J Eisen; T M Guenthner; D W Nebert
Journal:  J Biol Chem       Date:  1979-11-25       Impact factor: 5.157

4.  The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation.

Authors:  Laurie Prigent; Marc Robineau; Stéphane Jouneau; Claudie Morzadec; Laetitia Louarn; Laurent Vernhet; Olivier Fardel; Lydie Sparfel
Journal:  Eur J Immunol       Date:  2014-02-18       Impact factor: 5.532

5.  Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.

Authors:  Sharon Benzeno; Goutham Narla; Jorge Allina; George Z Cheng; Helen L Reeves; Michaela S Banck; Joseph A Odin; J Alan Diehl; Doris Germain; Scott L Friedman
Journal:  Cancer Res       Date:  2004-06-01       Impact factor: 12.701

6.  Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells.

Authors:  Robert T Taylor; Feng Wang; Erin L Hsu; Oliver Hankinson
Journal:  Toxicol Sci       Date:  2008-10-08       Impact factor: 4.849

7.  Mutation and cancer: statistical study of retinoblastoma.

Authors:  A G Knudson
Journal:  Proc Natl Acad Sci U S A       Date:  1971-04       Impact factor: 11.205

8.  The Ah locus: correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA.

Authors:  R H Tukey; R R Hannah; M Negishi; D W Nebert; H J Eisen
Journal:  Cell       Date:  1982-11       Impact factor: 41.582

Review 9.  AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions.

Authors:  Fumiaki Ohtake; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
Journal:  Biochem Pharmacol       Date:  2008-09-16       Impact factor: 5.858

10.  Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line.

Authors:  Gennifer D Goode; Billy R Ballard; H Charles Manning; Michael L Freeman; Yibin Kang; Sakina E Eltom
Journal:  Int J Cancer       Date:  2013-07-05       Impact factor: 7.396
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  22 in total

1.  Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice.

Authors:  Jiong Yan; Hung-Chun Tung; Sihan Li; Yongdong Niu; Wojciech G Garbacz; Peipei Lu; Yuhan Bi; Yanping Li; Jinhan He; Meishu Xu; Songrong Ren; Satdarshan P Monga; Robert F Schwabe; Da Yang; Wen Xie
Journal:  Gastroenterology       Date:  2019-06-03       Impact factor: 22.682

2.  And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses.

Authors:  Michael S Denison; Samantha C Faber
Journal:  Curr Opin Toxicol       Date:  2017-02

3.  Dioxin and the AH Receptor: Synergy of Discovery.

Authors:  Linda S Birnbaum
Journal:  Curr Opin Toxicol       Date:  2017-02-02

4.  Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization.

Authors:  Dario Corrada; Michael S Denison; Laura Bonati
Journal:  Mol Biosyst       Date:  2017-05-02

Review 5.  Aryl hydrocarbon receptor (AhR)-mediated signaling as a critical regulator of skeletal cell biology.

Authors:  Dima W Alhamad; Husam Bensreti; Jennifer Dorn; William D Hill; Mark W Hamrick; Meghan E McGee-Lawrence
Journal:  J Mol Endocrinol       Date:  2022-08-22       Impact factor: 4.869

6.  Inhalation of particulate matter containing free radicals leads to decreased vascular responsiveness associated with an altered pulmonary function.

Authors:  Ashlyn C Harmon; Alexandra Noël; Balamurugan Subramanian; Zakia Perveen; Merilyn H Jennings; Yi-Fan Chen; Arthur L Penn; Kelsey Legendre; Daniel B Paulsen; Kurt J Varner; Tammy R Dugas
Journal:  Am J Physiol Heart Circ Physiol       Date:  2021-08-20       Impact factor: 5.125

7.  Canonical and non-canonical aryl hydrocarbon receptor signaling pathways.

Authors:  Eric J Wright; Karen Pereira De Castro; Aditya D Joshi; Cornelis J Elferink
Journal:  Curr Opin Toxicol       Date:  2017-01-18

8.  2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) increases necroinflammation and hepatic stellate cell activation but does not exacerbate experimental liver fibrosis in mice.

Authors:  Cheri L Lamb; Giovan N Cholico; Xinzhu Pu; Gerald D Hagler; Kenneth A Cornell; Kristen A Mitchell
Journal:  Toxicol Appl Pharmacol       Date:  2016-09-28       Impact factor: 4.219

9.  A Review of the Functional Roles of the Zebrafish Aryl Hydrocarbon Receptors.

Authors:  Prarthana Shankar; Subham Dasgupta; Mark E Hahn; Robyn L Tanguay
Journal:  Toxicol Sci       Date:  2020-12-01       Impact factor: 4.849

Review 10.  Aryl hydrocarbon receptor: Its roles in physiology.

Authors:  Ziyue Kou; Wei Dai
Journal:  Biochem Pharmacol       Date:  2021-01-28       Impact factor: 5.858
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