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Literature DB >> 598416

Pharmacokinetics of tolmetin with and without concomitant administration of antacid in man.

J W Ayres, D J Weidler, J MacKichan, E Sakmar, M R Hallmark, E F Lemanowicz, J G Wagner.

Abstract

Entities: Chemical Species

Mesh：

Substances：
Antacids
Pyrroles
Tolmetin

Year: 1977 PMID： 598416 DOI： 10.1007/bf00561061

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

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14 in total

1. Time course and dose dependence of antacid effect on urine pH.

Authors: M Gibaldi; B Grundhofer; G Levy
Journal: J Pharm Sci Date: 1975-12 Impact factor: 3.534

2. ASPIRIN FORMULATION AND ABSORPTION RATE. II. INFLUENCE ON SERUM LEVELS OF TABLETS, ANTACIDS, AND SOLUTIONS.

Authors: S V LIEBERMAN; J H WOOD
Journal: J Pharm Sci Date: 1964-12 Impact factor: 3.534

3. Control of urine pH and its effect on sulfaethidole excretion in humans.

Authors: H B KOSTENBAUDER; J B PORTNOFF; J V SWINTOSKY
Journal: J Pharm Sci Date: 1962-11 Impact factor: 3.534

4. Linear and nonlinear assessment of tolmetin pharmacokinetics.

Authors: J W Ayres; D J Weidler; E Sakmar; J G Wagner
Journal: Res Commun Chem Pathol Pharmacol Date: 1977-08

5. Metabolism of tolmetin in rat, monkey, and man.

Authors: D D Sumner; P G Dayton; S A Cucinell; J Plostnieks
Journal: Drug Metab Dispos Date: 1975 Jul-Aug Impact factor: 3.922

6. Effect of antacids on pH of urine.

Authors: M Gibaldi; B Grundhofer; G Levy
Journal: Clin Pharmacol Ther Date: 1974-09 Impact factor: 6.875

7. A gas-liquid chromatographic method for the quantitative determination of tolmetin in plasma and tolmetin and its major metabolite in urine.

Authors: M L Selley; J Thomas; E J Triggs
Journal: J Chromatogr Date: 1974-07-17

8. Urine pH and salicylate therapy.

Authors: G Levy; J R Leonards
Journal: JAMA Date: 1971-07-05 Impact factor: 56.272

9. 5-Benzoyl-1-methylpyrrole-2-acetic acids as antiinflammatory agents.

Authors: J R Carson; D N McKinstry; S Wong
Journal: J Med Chem Date: 1971-07 Impact factor: 7.446

10. Absorption and excretion of tolemetin in man.

Authors: W A Cressman; G F Wortham; J Plostnieks
Journal: Clin Pharmacol Ther Date: 1976-02 Impact factor: 6.875

7 in total

1. Stepwise determination of multicompartment disposition and absorption parameters from extravascular concentration-time data. Application to mesoridazine, flurbiprofen, flunarizine, labetalol, and diazepam.

Authors: J G Wagner; D A Ganes; K K Midha; I Gonzalez-Younes; J C Sackellares; L D Olson; M B Affrime; J E Patrick
Journal: J Pharmacokinet Biopharm Date: 1991-08

Pharmacokinetics of tolmetin with and without concomitant administration of antacid in man.

1. Time course and dose dependence of antacid effect on urine pH.

2. ASPIRIN FORMULATION AND ABSORPTION RATE. II. INFLUENCE ON SERUM LEVELS OF TABLETS, ANTACIDS, AND SOLUTIONS.

3. Control of urine pH and its effect on sulfaethidole excretion in humans.

4. Linear and nonlinear assessment of tolmetin pharmacokinetics.

5. Metabolism of tolmetin in rat, monkey, and man.

6. Effect of antacids on pH of urine.

7. A gas-liquid chromatographic method for the quantitative determination of tolmetin in plasma and tolmetin and its major metabolite in urine.

8. Urine pH and salicylate therapy.

9. 5-Benzoyl-1-methylpyrrole-2-acetic acids as antiinflammatory agents.

10. Absorption and excretion of tolemetin in man.

1. Stepwise determination of multicompartment disposition and absorption parameters from extravascular concentration-time data. Application to mesoridazine, flurbiprofen, flunarizine, labetalol, and diazepam.

Review 2. Clinically significant drug interactions with antacids: an update.

Review 3. Tolmetin: a review of its pharmacological properties and therapeutic efficacy in rheumatic diseases.

4. Effect of food and various antacids on the absorption of tenoxicam.

Review 5. Antirheumatic drugs: clinical pharmacology and therapeutic use.

6. Bioavailability of ketoprofen in man with and without concomitant administration of aluminium phosphate.

Review 7. Clinical pharmacokinetics of non-steroidal anti-inflammatory drugs.