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Literature DB >> 59796

Leucocyte migration inhibition in myasthenia gravis. The effect of thymectomy.

Abstract

Cellular hypersensitivity in myasthenia gravis (MG) to the thymus, muscles and peripheral nerves was examined by the method of the leucocyte migration inhibition test. The group of MG patients without thymoma had inhibition of leucocyte migration by thymus antigens. After thymectomy, they had a normal value of leucocyte migration. However, in the group of MG patients with thymoma, the inhibition of leucocyte migration by thymus antigens was observed after thymectomy. No significant inhibition of leucocyte migration was observed using muscle and peripheral nerve antigens. Cellular immunity in myasthenia gravis and the pathogenesis of the disease was discussed.

Entities: Disease Species

Mesh：

Year: 1976 PMID： 59796 DOI： 10.1007/bf00316337

Source DB: PubMed Journal: J Neurol ISSN： 0340-5354 Impact factor: 4.849

27 in total

1. SEPARATION OF VIABLE LYMPHOCYTES FROM HUMAN BLOOD.

Authors: A S COULSON; D G CHALMERS
Journal: Lancet Date: 1964-02-29 Impact factor: 79.321

2. Changes in serum complement activity in patients with myasthenia gravis.

Authors: W L NASTUK; O J PLESCIA; K E OSSERMAN
Journal: Proc Soc Exp Biol Med Date: 1960-10

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Authors: D S RUSSELL
Journal: J Pathol Bacteriol Date: 1953-04

4. Studies in myasthenia gravis: demonstration of presence of immunofluorescence in serums correlated with clinical findings.

Authors: L B Weiner; K E Osserman
Journal: Ann N Y Acad Sci Date: 1966-01-26 Impact factor: 5.691

5. Studies in myasthenia gravis: cellular hypersensitivity to skeletal muscle.

Authors: L I Alpert; A Rule; M Norio; E Kott; P Kornfeld; K E Osserman
Journal: Am J Clin Pathol Date: 1972-12 Impact factor: 2.493

6. The in vitro transformation of thymocytes and lymphocytes from humans, rabbits and guinea-pigs and from thymomas.

Authors: S Knight; J Bradley; J J Oppenheim; N R Ling
Journal: Clin Exp Immunol Date: 1968-05 Impact factor: 4.330

Review 7. Myasthenia gravis as an autoimmune disease: clinical aspects.

Authors: J A Simpson
Journal: Ann N Y Acad Sci Date: 1966-01-26 Impact factor: 5.691

8. Studies in myasthenia gravis: effects of thymectomy. Results on 185 patients with nonthymomatous and thymomatous myasthenia gravis, 1941-1969.

Authors: A E Papatestas; L I Alpert; K E Osserman; R S Osserman; A E Kark
Journal: Am J Med Date: 1971-04 Impact factor: 4.965

Leucocyte migration inhibition in myasthenia gravis. The effect of thymectomy.

1. SEPARATION OF VIABLE LYMPHOCYTES FROM HUMAN BLOOD.

2. Changes in serum complement activity in patients with myasthenia gravis.

3. Histological changes in the striped muscles in myasthenia gravis.

4. Studies in myasthenia gravis: demonstration of presence of immunofluorescence in serums correlated with clinical findings.

5. Studies in myasthenia gravis: cellular hypersensitivity to skeletal muscle.

6. The in vitro transformation of thymocytes and lymphocytes from humans, rabbits and guinea-pigs and from thymomas.

Review 7. Myasthenia gravis as an autoimmune disease: clinical aspects.

8. Studies in myasthenia gravis: effects of thymectomy. Results on 185 patients with nonthymomatous and thymomatous myasthenia gravis, 1941-1969.

9. Delayed hypersensitivity to muscle and thymus in myasthenia gravis and polymyositis.

10. Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs.

1. Lymphocyte function in myasthenia gravis.

2. T and B lymphocytes in myasthenia gravis.