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Literature DB >> 5966287

Control of haem synthesis by feedback inhibition on human-erythrocyte delta-aminolaevulate dehydratase.

P Calissano, D Bonsignore, C Cartasegna.

Abstract

The action of haem, haemoglobin and other haemoproteins on crude and purified delta-aminolaevulate dehydratase of human erythrocyte is described. The results show a feedback inhibition by haem of porphyrin synthesis at the level of erythrocyte delta-aminolaevulate dehydratase. Some kinetic characteristics of this inhibition are described.

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Year: 1966 PMID： 5966287 PMCID： PMC1270139 DOI： 10.1042/bj1010550

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

7 in total

1. delta-aminolaevulate dehydratase from Rhodopseudomonas spheroides.

Authors: B F BURNHAM; W S PIERCE; K R WILLIAMS; M H BOYER; C K KIRBY
Journal: Biochem J Date: 1963-06 Impact factor: 3.857

2. THE EFFECT OF HEMIN ON THE SYNTHESIS OF GLOBIN.

Authors: G P BRUNS; I M LONDON
Journal: Biochem Biophys Res Commun Date: 1965-01-18 Impact factor: 3.575

3. CONTROL OF HEME SYNTHESIS BY FEEDBACK INHIBITION.

Authors: D KARIBIAN; I M LONDON
Journal: Biochem Biophys Res Commun Date: 1965-01-18 Impact factor: 3.575

4. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

5. The purification and properties of ALA dehydratase from human erythrocytes.

Authors: P Calissano; C Cartasegna; M Matteini
Journal: Ital J Biochem Date: 1966 Jan-Feb

6. [A simple method of determining delta-amino-levulino-dehydratase in the blood. Behavior of the enzyme in lead poisoning].

Authors: D Bonsignore; P Calissano; C Cartasegna
Journal: Med Lav Date: 1965-03 Impact factor: 1.275

7. [On the mechanism of erythrocyte ALA dehydratase inhibition by lead].

Authors: D Bonsignore; P Calissano; C Cartasegna
Journal: Med Lav Date: 1965-11 Impact factor: 1.275

7 in total

6 in total

6. Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intravenous infusions of hematin.

Authors: H L Bonkowsky; D P Tschudy; A Collins; J Doherty; I Bossenmaier; R Cardinal; C J Watson
Journal: Proc Natl Acad Sci U S A Date: 1971-11 Impact factor: 11.205

6 in total

Control of haem synthesis by feedback inhibition on human-erythrocyte delta-aminolaevulate dehydratase.

1. delta-aminolaevulate dehydratase from Rhodopseudomonas spheroides.

2. THE EFFECT OF HEMIN ON THE SYNTHESIS OF GLOBIN.

3. CONTROL OF HEME SYNTHESIS BY FEEDBACK INHIBITION.

4. Protein measurement with the Folin phenol reagent.

5. The purification and properties of ALA dehydratase from human erythrocytes.

6. [A simple method of determining delta-amino-levulino-dehydratase in the blood. Behavior of the enzyme in lead poisoning].

7. [On the mechanism of erythrocyte ALA dehydratase inhibition by lead].

1. Synthesis of haem and cytochrome c prosthetic group from delta-aminolaevulinate by the cell sap from rat liver.

2. [Erythrocyte delta-aminolevulinic acid metabolism as modified by heme metabolites].

3. Delta-aminolaevulinate dehydratase, the regulatory enzyme of the haem-biosynthetic pathway in Neurospora crassa.

4. Aberration of porphyrin metabolism in iron-deficient anaemic rats.

5. Purification and general properties of delta-aminolaevulate dehydratase from Nicotiana tabacum L.

6. Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intravenous infusions of hematin.