Literature DB >> 596315

Inhibitory effect of enkephalins on contractions of the guinea-pig ileum elicited by PGE1.

R Jaques.   

Abstract

Methionine-enkephalin and leucine-enkephalin (m-enk and 1-enk) as well as D-Ala2-methionine-enkephalin amide have been shown to antagonize contractions of the isolated guinea-pig intestine elicited by PGE1, the last mentioned being the most potent of the three. The inhibitory effect of these pentapeptides is abolished by naloxone.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 596315     DOI： 10.1007/bf01969562

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  12 in total

1.  Purification and properties of enkephalin - the possible endogenous ligand for the morphine receptor.

Authors:  J Hughes; T Smith; B Morgan; L Fothergill
Journal:  Life Sci       Date:  1975-06-15       Impact factor: 5.037

2.  Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine.

Authors:  J Hughes
Journal:  Brain Res       Date:  1975-05-02       Impact factor: 3.252

3.  Synthesis and opioid activities of stereoisomers and other D-amino acid analogs of methionine-enkephalin.

Authors:  D H Coy; A J Kastin; A V Schally; O Morin; N G Caron; F Labrie; J M Walker; R Fertel; G G Berntson; C A Sandman
Journal:  Biochem Biophys Res Commun       Date:  1976-12-06       Impact factor: 3.575

4.  Analgesia induced in vivo by central administration of enkephalin in rat.

Authors:  J D Belluzzi; N Grant; V Garsky; D Sarantakis; C D Wise; L Stein
Journal:  Nature       Date:  1976-04-15       Impact factor: 49.962

5.  Receptor binding and pharmacological activity of opiates in the guinea-pig intestine.

Authors:  I Creese; S H Snyder
Journal:  J Pharmacol Exp Ther       Date:  1975-07       Impact factor: 4.030

6.  Cross tolerance between morphine and methionine-enkephalin.

Authors:  A A Waterfield; J Hughes; H W Kosterlitz
Journal:  Nature       Date:  1976-04-15       Impact factor: 49.962

7.  A simple in vitro method of characterizing narcotic antagonists.

Authors:  M Rüegg; R Jaques
Journal:  Experientia       Date:  1972-12-15

8.  Release of prostaglandins by bradykinin as an intrinsic mechanism of its algesic effect.

Authors:  F Lembeck; H Popper; H Juan
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-07       Impact factor: 3.000

9.  Identification of two related pentapeptides from the brain with potent opiate agonist activity.

Authors:  J Hughes; T W Smith; H W Kosterlitz; L A Fothergill; B A Morgan; H R Morris
Journal:  Nature       Date:  1975-12-18       Impact factor: 49.962

10.  Isolation of a novel endogenous opiate analgesic from human blood.

Authors:  C B Pert; A Pert; J F Tallman
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205
View more
  2 in total

1.  Effect of methionine-enkephalin and naloxone on bombesin-stimulated gastric acid secretion, gastrin, and pancreatic polypeptide release in the dog.

Authors:  A Materia; B M Jaffe; I M Modlin; A Sank; D Albert
Journal:  Ann Surg       Date:  1982-07       Impact factor: 12.969

2.  Potentiation of histamine-induced itch and flare responses in human skin by the enkephalin analogue FK-33-824, beta-endorphin and morphine.

Authors:  B Fjellner; O Hägermark
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.