Literature DB >> 595585

Human chorionic gonadotropin (HCG) in the treatment of obesity: a critical assessment of the Simeons method.

F L Greenway, G A Bray.   

Abstract

Injections of human chorionic gonadotropin (HCG) have been claimed to aid in weight reduction by reducing hunger, and affecting mood as well as aiding in localized (spot) reduction. We have tested these claims in a double-blind randomized trial using injections of HCG or placebo. Weight loss was identical between the two groups, and there was no evidence for differential effects on hunger, mood or localized body measurements. Placebo injections, therefore, appear to be as effective as HCG in the treatment of obesity.

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Year:  1977        PMID： 595585      PMCID： PMC1237915     

Source DB:  PubMed          Journal:  West J Med        ISSN： 0093-0415


  9 in total

1.  The action of chorionic gonadotrophin in the obese.

Authors:  S CARNE
Journal:  Lancet       Date:  1961-12-09       Impact factor: 79.321

2.  The action of chorionic gonadotrophin in the obese.

Authors:  A T SIMEONS
Journal:  Lancet       Date:  1954-11-06       Impact factor: 79.321

3.  Effect of human chorionic gonadotrophin on weight loss, hunger, and feeling of well-being.

Authors:  W L Asher; H W Harper
Journal:  Am J Clin Nutr       Date:  1973-02       Impact factor: 7.045

4.  Chorionic gonadotropin and obesity?

Authors:  M J Albrink
Journal:  Am J Clin Nutr       Date:  1969-06       Impact factor: 7.045

5.  Validation of the multiple affect adjective check list in clinical situations.

Authors:  M Zuckerman; B Lubin; S Robins
Journal:  J Consult Psychol       Date:  1965-12

Review 6.  Pharmacological approaches to treating the obese patient.

Authors:  G A Bray; F L Greenway
Journal:  Clin Endocrinol Metab       Date:  1976-07

7.  Direct measurement of the anorectic activity of diethylpropion (Tenuate Dospan).

Authors:  J T Silverstone; P Turner; P L Humpherson
Journal:  J Clin Pharmacol J New Drugs       Date:  1968 May-Jun

8.  Chorionic gonadotropin in weight control. A double-blind crossover study.

Authors:  R L Young; R J Fuchs; M J Woltjen
Journal:  JAMA       Date:  1976-11-29       Impact factor: 56.272

9.  Ineffectiveness of human chorionic gonadotropin in weight reduction: a double-blind study.

Authors:  M R Stein; R E Julis; C C Peck; W Hinshaw; J E Sawicki; J J Deller
Journal:  Am J Clin Nutr       Date:  1976-09       Impact factor: 7.045
  9 in total
  6 in total

Review 1.  Pharmacological approaches for the treatment of obesity.

Authors:  José-Antonio Fernández-López; Xavier Remesar; Màrius Foz; Marià Alemany
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 2.  Obesity. Part II--Treatment.

Authors:  G A Bray; D S Gray
Journal:  West J Med       Date:  1988-11

3.  The effect of human chorionic gonadotropin (HCG) in the treatment of obesity by means of the Simeons therapy: a criteria-based meta-analysis.

Authors:  G K Lijesen; I Theeuwen; W J Assendelft; G Van Der Wal
Journal:  Br J Clin Pharmacol       Date:  1995-09       Impact factor: 4.335

4.  Human chorionic gonadotropin is of no value in the management of obesity.

Authors:  C L Birmingham; K C Smith
Journal:  Can Med Assoc J       Date:  1983-05-15       Impact factor: 8.262

Review 5.  Controversies in plastic surgery: suction-assisted lipectomy (SAL) and the hCG (human chorionic gonadotropin) protocol for obesity treatment.

Authors:  T Vogt; D Belluscio
Journal:  Aesthetic Plast Surg       Date:  1987       Impact factor: 2.326

6.  Effect of weight reduction on cardiovascular risk factors and CD34-positive cells in circulation.

Authors:  Nina A Mikirova; Joseph J Casciari; Ronald E Hunninghake; Margaret M Beezley
Journal:  Int J Med Sci       Date:  2011-08-01       Impact factor: 3.738
  6 in total

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