Literature DB >> 593991

Prostaglandins and model aspects of thrombosis.

J Westwick.   

Abstract

The possible role of prostaglandins (PGs) in thrombosis was determined by examining their effects in models of thrombosis which included platelet aggregation (in vitro), blood flow (in vivo) and thrombus formation (in vivo). It was found that blood flow and thrombosis can be effectively modulated by the various types of prostaglandins produced by the blood and the vascular tissue.

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Year:  1977        PMID： 593991      PMCID： PMC2496836          DOI： 10.1136/pgmj.53.625.663

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  11 in total

1.  Proceedings: The effect of sulphinpyrazone, sodium aspirin and oxprenolol on the formation of arterial platelet thrombi.

Authors:  G P Lewis; J Westwick
Journal:  Br J Pharmacol       Date:  1975-10       Impact factor: 8.739

2.  THE AGGREGATION OF BLOOD PLATELETS.

Authors:  G V BORN; M J CROSS
Journal:  J Physiol       Date:  1963-08       Impact factor: 5.182

3.  The effect of pulmonary metabolites of prostaglandins E1, E2 and F2alpha on ADP-induced aggregation of human and rabbit platelets [proceedings].

Authors:  J Westwick
Journal:  Br J Pharmacol       Date:  1976-10       Impact factor: 8.739

4.  Microcirculatory effects of prostaglandins E1, E2, and A1 in the rat mesentery and cremaster muscle.

Authors:  E J Messina; R Weiner; G Kaley
Journal:  Microvasc Res       Date:  1974-07       Impact factor: 3.514

5.  Prostaglandin D2 inhibits the aggregation of human platelets.

Authors:  J B Smith; M J Silver; C M Ingerman; J J Kocsis
Journal:  Thromb Res       Date:  1974-09       Impact factor: 3.944

Review 6.  The prostaglandins: a family of biologically active lipids.

Authors:  S Bergström; L A Carlson; J R Weeks
Journal:  Pharmacol Rev       Date:  1968-03       Impact factor: 25.468

7.  Effect of prostaglandin E1 on platelet behaviour in vitro and in vivo.

Authors:  P R Emmons; J R Hampton; M J Harrison; A J Honour; J R Mitchell
Journal:  Br Med J       Date:  1967-05-20

8.  The chemical structure of prostaglandin X (prostacyclin).

Authors:  N Whittaker; S Bunting; J Salmon; S Moncada; J R Vane; R A Johnson; D R Morton; J H Kinner; R R Gorman; J C McGuire; F F Sun
Journal:  Prostaglandins       Date:  1976-12

9.  An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation.

Authors:  S Moncada; R Gryglewski; S Bunting; J R Vane
Journal:  Nature       Date:  1976-10-21       Impact factor: 49.962

10.  Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Authors:  M Hamberg; J Svensson; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205
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  1 in total

1.  Effects of prostaglandins E2 and I2 on human lymphocyte transformation in the presence and absence of inhibitors of prostaglandin biosynthesis.

Authors:  D Gordon; D C Henderson; J Westwick
Journal:  Br J Pharmacol       Date:  1979-09       Impact factor: 8.739
  1 in total

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