Literature DB >> 593987

Prostaglandins and the lung.

J Morley.   

Abstract

Evidence exists implicating prostaglandins as mediators of asthma and of chronic inflammation in the lung. In addition to their spasmogenic effects, PGs are also potent in vitro regulators of mediator secretion by basophils, mast cells, or lymphocytes. These regulatory effects of E-series PGs may have considerable significance in drug design and evaluation in both asthma and chronic inflammation.

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Year:  1977        PMID： 593987      PMCID： PMC2496817          DOI： 10.1136/pgmj.53.625.652

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  9 in total

1.  Corticosteroids inhibit prostaglandin production by rheumatiod synovia.

Authors:  F Kantrowitz; D R Robinson; M B McGuire; L Levine
Journal:  Nature       Date:  1975-12-25       Impact factor: 49.962

2.  Defective PGE reactivity in leucocytes of multiple sclerosis patients.

Authors:  P J Kirby; J Morley; J R Ponsford; W I McDonald
Journal:  Prostaglandins       Date:  1976-04

3.  Control of lymphokine secretion by prostaglandins.

Authors:  D Gordon; M A Bray; J Morley
Journal:  Nature       Date:  1976-07-29       Impact factor: 49.962

4.  Prostaglandins as potentiators of increased vascular permeability in inflammation.

Authors:  T J Williams; J Morley
Journal:  Nature       Date:  1973-11-23       Impact factor: 49.962

5.  Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.

Authors:  A Szczeklik; R J Gryglewski; G Czerniawska-Mysik
Journal:  Br Med J       Date:  1975-01-11

6.  Increased plasma levels of 15-keto-13,14-dihydro-prostaglandin F2X after allergen-provoked asthma in man.

Authors:  K Gréen; P Hedqvist; N Svanborg
Journal:  Lancet       Date:  1974-12-14       Impact factor: 79.321

Review 7.  The mode of action of aspirin and similar compounds.

Authors:  J R Vane
Journal:  J Allergy Clin Immunol       Date:  1976-12       Impact factor: 10.793

8.  Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma.

Authors:  A A Mathé; P Hedqvist; A Holmgren; N Svanborg
Journal:  Br Med J       Date:  1973-01-27

9.  Macrophage responses to mouldy hay dust, Micropolyspora faeni and zymosan, activators of complement by the alternative pathway.

Authors:  H U Schorlemmer; J H Edwards; P Davies; A C Allison
Journal:  Clin Exp Immunol       Date:  1977-02       Impact factor: 4.330
  9 in total

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