Literature DB >> 5938643

Biochemical studies of toxic agents. Metabolic ring-fission of cis- and trans-acenaphthene-1,2-diol.

R P Hopkins, L Young.   

Abstract

1. The metabolism of cis- and trans-acenaphthene-1,2-diol has been studied after the administration of these compounds to rats by subcutaneous injection and by stomach tube. 2. 1,8-Naphthalic acid has been isolated as its anhydride from the urine of the dosed animals. 3. A spectrophotometric method for the determination of free and conjugated 1,8-naphthalic acid in urine has been developed and has been used in the study of the metabolism of the acenaphthene-1,2-diols. 4. The urine of rats dosed with cis-acenaphthene-1,2-diol by subcutaneous injection was shown by paper chromatography to contain both cis- and trans-acenaphthene-1,2-diol. Similar findings were obtained after the subcutaneous injection of trans-acenaphthene-1,2-diol.

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Year:  1966        PMID: 5938643      PMCID: PMC1264788          DOI: 10.1042/bj0980019

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  10 in total

1.  MECHANISM OF BETA-KETOADIPATE FORMATION BY BACTERIA.

Authors:  L N ORNSTON; R Y STANIER
Journal:  Nature       Date:  1964-12-26       Impact factor: 49.962

2.  Metabolism of polycyclic compounds. 21. The metabolism of phenanthrene in rabbits and rats: dihydrodihydroxy compounds and related glucosiduronic acids.

Authors:  E BOYLAND; P SIMS
Journal:  Biochem J       Date:  1962-09       Impact factor: 3.857

3.  Biochemical studies of toxic agents. 13. The metabolism of acenaphthylene.

Authors:  R P HOPKINS; C J BROOKS; L YOUNG
Journal:  Biochem J       Date:  1962-03       Impact factor: 3.857

4.  The properties of maleylacetoacetate, the initial product of homogentisate oxidation in liver.

Authors:  W E KNOX; S W EDWARDS
Journal:  J Biol Chem       Date:  1955-10       Impact factor: 5.157

5.  Biochemical studies of toxic agents. 9. The metabolic conversion of indene into cis- and trans- indane-1: 2-diol.

Authors:  C J BROOKS; L YOUNG
Journal:  Biochem J       Date:  1956-06       Impact factor: 3.857

6.  The metabolic conversion of naphthalene to 1:2-dihydronaphthalene-1:2-diol.

Authors:  L Young
Journal:  Biochem J       Date:  1947       Impact factor: 3.857

7.  Metabolism of polycyclic compounds: Production of dihydroxydihydroanthracene from anthracene.

Authors:  E Boyland; A A Levi
Journal:  Biochem J       Date:  1935-12       Impact factor: 3.857

8.  Metabolism of polycyclic compounds. 5. Formation of 1:2-dihydroxy-1:2-dihydronaphthalenes.

Authors:  J Booth; E Boyland
Journal:  Biochem J       Date:  1949       Impact factor: 3.857

9.  Metabolism of polycyclic compounds. 6. Conversion of phenanthrene into dihydroxydihydrophenanthrenes.

Authors:  E BOYLAND; G WOLF
Journal:  Biochem J       Date:  1950 Jun-Jul       Impact factor: 3.857

10.  [On the chemistry of benzene glycol. VI. Metabolism of benzene glycols and muconic dialdehydes].

Authors:  I TOMIDA; M NAKAJIMA
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1960-05-31
  10 in total
  9 in total

1.  Investigation of the metabolic oxidation of acenaphthen-1-ol.

Authors:  C J Simmons; R P Hopkins; P Callaghan
Journal:  Biochem J       Date:  1971-09       Impact factor: 3.857

2.  Studies on beta-glucanases. Some properties of a bacterial endo-beta-(1 leads to 3)-glucanase system.

Authors:  D J Manners; G Wilson
Journal:  Biochem J       Date:  1973-09       Impact factor: 3.857

3.  Bacterial oxidation of the polycyclic aromatic hydrocarbons acenaphthene and acenaphthylene.

Authors:  M J Schocken; D T Gibson
Journal:  Appl Environ Microbiol       Date:  1984-07       Impact factor: 4.792

4.  Cyclitol glucosides and their role in the synthesis of a glucan from uridine diphosphate glucose in Phaseolus aureus. Characterization of some cyclitol glucosides and their synthesis.

Authors:  J Kemp; B C Loughman
Journal:  Biochem J       Date:  1974-07       Impact factor: 3.857

5.  The structure of a beta-(1 leads to 3)-D-glucan from yeast cell walls.

Authors:  D J Manners; A J Masson; J C Patterson
Journal:  Biochem J       Date:  1973-09       Impact factor: 3.857

6.  The incorporation of long-chain fatty acids into phospholipids of respiring slices of rat cerebrum.

Authors:  G R Webster
Journal:  Biochem J       Date:  1967-01       Impact factor: 3.857

7.  Fungal metabolism of acenaphthene by Cunninghamella elegans.

Authors:  J V Pothuluri; J P Freeman; F E Evans; C E Cerniglia
Journal:  Appl Environ Microbiol       Date:  1992-11       Impact factor: 4.792

8.  Microsomal ring-fission of cis- and trans-acenaphthene-1,2-diol.

Authors:  R P Hopkins
Journal:  Biochem J       Date:  1968-07       Impact factor: 3.857

9.  The structure of a beta-(1--6)-D-glucan from yeast cell walls.

Authors:  D J Manners; A J Masson; J C Patterson; H Björndal; B Lindberg
Journal:  Biochem J       Date:  1973-09       Impact factor: 3.857

  9 in total

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