Literature DB >> 593442

Temperature dependence of phalloidin response in isolated rat hepatocytes.

M Frimmer, U Rufeger.   

Abstract

Below 21 degrees C isolated hepatocytes are insensitive to phalloidin. Between 21 and 30 degrees C the amount of affected cells increases to nearly maximal values, whereas a further rise of the temperature has little additional effect. These findings suggest that phase transition of membranal lipids might be responsible for the unusual temperature characteristics. The fluidity of lipids seems to control an early step of the phalloidin response.

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Year:  1977        PMID： 593442     DOI： 10.1007/bf00505051

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  10 in total

1.  Electron microscopy of isolated rat hepatocytes before and after treatment with phalloidin.

Authors:  E Weiss; I Sterz; M Frimmer; R Kroker
Journal:  Beitr Pathol       Date:  1973-12

2.  Temperature dependence of potassium depletion in the phalloidin poisoned perfused rat liver.

Authors:  M Frimmer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

3.  The mode of action of phalloidin: demonstration of rapid deformation of isolated hepatocytes by scanning electron microscopy.

Authors:  M Frimmer; R Kroker; J Porstendörfer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

4.  [Phalloidin antagonists. 2. Protective effect of disilybine in phalloidin poisoning of isolated hepatocytes].

Authors:  V E Petzinger; J Homann; M Frimmer
Journal:  Arzneimittelforschung       Date:  1975-04

5.  The role of plasma membranes in hepatotoxic effects.

Authors:  M Frimmer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977       Impact factor: 3.000

6.  Transient desensibilization of isolated hepatocytes against phalloidin by treatment with phospholipase A.

Authors:  E Petzinger; U Rufeger; M Frimmer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978 Jan-Feb       Impact factor: 3.000

7.  Trypsin protection of hepatocytes against phalloidin.

Authors:  M Frimmer; E Petzinger; U Rufeger; L B Veil
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-11       Impact factor: 3.000

8.  [Phalloidin antagonists 4th communication: Thioctic acid, SH-compounds, rifampicin, choleretics, dexamethasone, estradiol, unspecific inhibitors, and ineffective compounds (author's transl)].

Authors:  M Frimmer; E Petzinger; J Homann
Journal:  Arzneimittelforschung       Date:  1975

9.  Scanning electron microscopic studies on the cytolytic effect of phallolysin on isolated rat hepatocytes and AS-30 D hepatoma cells.

Authors:  E Petzinger; R Seeger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-12       Impact factor: 3.000

10.  High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

Authors:  M N Berry; D S Friend
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539
  10 in total
  1 in total

1.  Energy linked uptake of demethylphalloin by isolated rat liver cells.

Authors:  E Petzinger; M Frimmer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-04       Impact factor: 3.000
  1 in total

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