| Literature DB >> 5919441 |
G Weissmann, G Sessa, A W Bernheimer.
Abstract
Staphylococcal alpha-toxin induces the release of previously sequestered anions or glucose from artificial phospholipid spherules, an effect abolished by specific antitoxin. Alphatoxin resembles streptolysin S in releasing anions or glucose from spherules prepared without cholesterol, and can be distinguished from the membrane-active polyene amphotericin B, which preferentially disrupts spherules containing cholesterol. It may affect biological structures by a similiar interaction with membrane phospholipids.Entities:
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Year: 1966 PMID： 5919441 DOI： 10.1126/science.154.3750.772
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728