Literature DB >> 5918714

N-cyclohexyl linoleamide: metabolism and cholesterol-lowering effect in rats.

H Nakatani, H Fukushima, A Wakimura, M Endo.   

Abstract

More than half of orally administered N-cyclohexyl linoleamide-car-boxyl-C(14) yl-CI was recovered from feces of rats, and 30 to 50 percent of the absorbed carbon-14 activity was excreted in urine. N-Cyclohexyl linoleamide had an inhibitory eflect on the absorption of cholesterol from the thoracic duct and caused a decrease in the deposition of cholesterol in the livers of rats that had been fed cholesterol.

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Year:  1966        PMID: 5918714     DOI: 10.1126/science.153.3741.1267

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

1.  Arylsulfonate esters as hypocholesteremic agents: III. Mechanism of action studies.

Authors:  J E MacNintch; R A Harris; W M Grogan; C L Villemez; F W Quackenbush
Journal:  Lipids       Date:  1977-10       Impact factor: 1.880

2.  Inhibition of cholesterol absorption by (-)N-[alpha-phenyl-beta-(p-tolyl)ethyl] linoleamide in rats.

Authors:  A Nagata; H Nakatani; K Toki
Journal:  Lipids       Date:  1976-03       Impact factor: 1.880

3.  Effect of (-)N-[alpha-phenyl-beta-(p-tolyl)ethyl] linoleamide on lipid levels in serum and liver in cholesterol-fed rats.

Authors:  A Nagata; S Aono; H Nakatani
Journal:  Lipids       Date:  1976-03       Impact factor: 1.880

4.  Linoleic acid amides: effect on cholesteremia and atherosclerosis.

Authors:  D Kritchevsky; S A Tepper; J A Story
Journal:  Lipids       Date:  1977-01       Impact factor: 1.880

  4 in total

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