| Literature DB >> 588591 |
Abstract
Sequence studies of an alpha-helical peptide antifreeze isolated from winter flounder have revealed the presence of clusters of polar amino acids separated by long sequences of alanine. Most of the polar residues are threonine and aspartate and are separated by 4.5 A, a repeat distance that also separates the oxygens in the ice lattice along the a-axis of an ice crystal. Such a lattice match suggests that the peptide binds to ice by means of hydrogen binding.Entities:
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Year: 1977 PMID： 588591 DOI： 10.1016/0005-2795(77)90395-6
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002