Literature DB >> 5866715

The metabolism of thalidomide: the spontaneous hydrolysis of thalidomide in solution.

H Schumacher, R L Smith, R T Williams.   

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Year:  1965        PMID： 5866715      PMCID： PMC1510736          DOI： 10.1111/j.1476-5381.1965.tb02053.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


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  3 in total

1.  [On the behavior of thalidomide in the organism. 1].

Authors:  R BECKMANN
Journal:  Arzneimittelforschung       Date:  1962-11

2.  The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species.

Authors:  H Schumacher; R L Smith; R T Williams
Journal:  Br J Pharmacol Chemother       Date:  1965-10

3.  [On the quantitative determination and the qualitative demonstration of N-phthalylglutamic acid imide (thalidomide)].

Authors:  R BECKMANN; H H KAMPF
Journal:  Arzneimittelforschung       Date:  1961-01
  3 in total
  22 in total

1.  Transport of thalidomide by the human intestinal caco-2 monolayers.

Authors:  Shufeng Zhou; Yan Li; Phillip Kestell; Peter Schafer; Eli Chan; James W Paxton
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2005 Jan-Jun       Impact factor: 2.441

2.  [What is the relevance of various previous lesions of the peripheral nervous system to a thalidomide polyneuropathy?].

Authors:  G P Liebaldt; F Broser
Journal:  Z Neurol       Date:  1971

3.  Thalidomide neuropathy: a clinical electrophysiological, and histological follow-up study.

Authors:  P M Fullerton; D J O'Sullivan
Journal:  J Neurol Neurosurg Psychiatry       Date:  1968-12       Impact factor: 10.154

Review 4.  Thalidomide and derivatives: immunological investigations of tumour necrosis factor-alpha (TNF-alpha) inhibition suggest drugs capable of selective gene regulation.

Authors:  S M McHugh; T L Rowland
Journal:  Clin Exp Immunol       Date:  1997-11       Impact factor: 4.330

5.  The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species.

Authors:  H Schumacher; R L Smith; R T Williams
Journal:  Br J Pharmacol Chemother       Date:  1965-10

6.  Chemical stabilities and biological activities of thalidomide and its N-alkyl analogs.

Authors:  Colleen Goosen; Timothy J Laing; Jeanetta du Plessis; Theunis C Goosen; Tharaknath B Rao; Gordon L Flynn
Journal:  Pharm Res       Date:  2002-08       Impact factor: 4.200

7.  Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity.

Authors:  L G Corral; G W Muller; A L Moreira; Y Chen; M Wu; D Stirling; G Kaplan
Journal:  Mol Med       Date:  1996-07       Impact factor: 6.354

8.  The fate of[14C]thalidomide in the pregnant rabbit.

Authors:  S Fabro; R L Smith; R T Williams
Journal:  Biochem J       Date:  1967-08       Impact factor: 3.857

9.  The fate of the hydrolysis products of thalidomide in the pregnant rabbit.

Authors:  S Fabro; R L Smith; R T Williams
Journal:  Biochem J       Date:  1967-08       Impact factor: 3.857

10.  The rise, fall and subsequent triumph of thalidomide: lessons learned in drug development.

Authors:  Waqas Rehman; Lisa M Arfons; Hillard M Lazarus
Journal:  Ther Adv Hematol       Date:  2011-10
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