Literature DB >> 5816327

Maturation of renal organic acid transport: substrate stimulation by penicillin.

G H Hirsch, J B Hook.   

Abstract

Renal p-aminohippurate transport in rabbits increased rapidly from birth to 4 weeks of age and then declined to that observed in adults. Penicillin administration to pregnant does or newborn rabbits stimulated the developing transport system, but did not increase the peak observed at 4 weeks. Therefore the continued presence of substrate (penicillin) during development significantly enhances the rate of maturation.

Entities:  

Mesh:

Substances:

Year:  1969        PMID: 5816327     DOI: 10.1126/science.165.3896.909

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  9 in total

Review 1.  Pharmacokinetics in neonatal prescribing: evidence base, paradigms and the future.

Authors:  Kate O'Hara; Ian M R Wright; Jennifer J Schneider; Alison L Jones; Jennifer H Martin
Journal:  Br J Clin Pharmacol       Date:  2015-10-26       Impact factor: 4.335

Review 2.  The systems biology of uric acid transporters: the role of remote sensing and signaling.

Authors:  Sanjay K Nigam; Vibha Bhatnagar
Journal:  Curr Opin Nephrol Hypertens       Date:  2018-07       Impact factor: 2.894

Review 3.  Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part II).

Authors:  J B Besunder; M D Reed; J L Blumer
Journal:  Clin Pharmacokinet       Date:  1988-05       Impact factor: 6.447

4.  Enhancement of p-aminohippurate accumulation in renal cortical slices after repeated administrations of various organic anionic drugs to rats of different ages.

Authors:  M Stopp; R Hartwich; H Bräunlich
Journal:  Experientia       Date:  1978-11-15

5.  Methyldopa kinetics before and after ingestion of methyldopa for eight weeks.

Authors:  N R Campbell; A Skerjanec; Y Tam; S Robertson; E Burgess
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

6.  Chlorinated hydrocarbon insecticides: recent animal data of potential significance for man.

Authors:  D J Ecobichon
Journal:  Can Med Assoc J       Date:  1970-10-10       Impact factor: 8.262

7.  Effect of substrate pretreatment on renal organic ion transport in the adult rat.

Authors:  D G Pegg; K M McCormack; J B Hook
Journal:  Experientia       Date:  1976-10-15

8.  Use of the tissue slice technique for evaluation of renal transport processes.

Authors:  W O Berndt
Journal:  Environ Health Perspect       Date:  1976-06       Impact factor: 9.031

9.  Perinatal nephropathies.

Authors:  J E Gibson
Journal:  Environ Health Perspect       Date:  1976-06       Impact factor: 9.031

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.