Literature DB >> 135696

Effect of substrate pretreatment on renal organic ion transport in the adult rat.

D G Pegg, K M McCormack, J B Hook.   

Abstract

The ability of renal cortical slices to accumulate PAH and NMN was not significantly affected by pretreatment of adult rats with large doses of PAH. Pretreatment of adult rats with THAM significantly increased PAH accumulation but had no effect on NMN. Inulin and PAH clearance and filtration fraction were significantly decreased by PAH pretreatment but unaffected by THAM pretreatment. The effects of pretreatment on transport are probably due to non-specific toxicity.

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Year:  1976        PMID: 135696     DOI: 10.1007/bf01953113

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  The effect of potassium dichromate on renal tubular transport processes.

Authors:  W O Berndt
Journal:  Toxicol Appl Pharmacol       Date:  1975-04       Impact factor: 4.219

2.  THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN.

Authors:  H W Smith; N Finkelstein; L Aliminosa; B Crawford; M Graber
Journal:  J Clin Invest       Date:  1945-05       Impact factor: 14.808

3.  Renal tubular transport: accumulation of p-aminohippurate by rabbit kidney slices.

Authors:  R J CROSS; J V TAGGART
Journal:  Am J Physiol       Date:  1950-04-01

4.  [Stimulation of the tubular transport of organic bases in rats of different ages].

Authors:  H Bräunlich; K Luther; S Rudolph
Journal:  Experientia       Date:  1974-11-15

5.  In vitro analysis of organic ion transport in renal cortex of the newborn rat.

Authors:  J K Kim; G H Hirsch; J B Hook
Journal:  Pediatr Res       Date:  1972-07       Impact factor: 3.756

6.  [Acceleration of renal excretion of p-aminohippuric acid in rats of various ages through repeated administration of foreign substances].

Authors:  G Bernhardt; H Bräunlich; C Dietze; W Lungershausen; R Schade
Journal:  Acta Biol Med Ger       Date:  1973

7.  Filtration fraction and extraction of PAH during neonatal period in the rat.

Authors:  M Horster; J E Lewy
Journal:  Am J Physiol       Date:  1970-10

8.  Effect of gentamicin on renal function in the rat.

Authors:  L Cohen; R Lapkin; G J Kaloyanides
Journal:  J Pharmacol Exp Ther       Date:  1975-04       Impact factor: 4.030

9.  Maturation of renal organic acid transport: substrate stimulation by penicillin and p-aminohippurate (PAH).

Authors:  G H Hirsch; J B Hook
Journal:  J Pharmacol Exp Ther       Date:  1970-01       Impact factor: 4.030

10.  Maturation of renal organic acid transport: substrate stimulation by penicillin.

Authors:  G H Hirsch; J B Hook
Journal:  Science       Date:  1969-08-29       Impact factor: 47.728

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  1 in total

1.  Enhancement of p-aminohippurate accumulation in renal cortical slices after repeated administrations of various organic anionic drugs to rats of different ages.

Authors:  M Stopp; R Hartwich; H Bräunlich
Journal:  Experientia       Date:  1978-11-15
  1 in total

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