Literature DB >> 5810979

Vitamin B 12 excretion by the rat small intestine.

C A Loehry, B Creamer.   

Abstract

Two phases of intestinal excretion are demonstrated after a parenteral dose of (58)Co vitamin B(12). The first phase was maximal immediately after injection, and was related to plasma radioactivity. The second phase was delayed 36 to 48 hours and was related to labelled cells reaching the tips of the villi. The loss of vitamin B(12) through increased exudation and rapid cell exfoliation together with failure of reabsorption may play a part in the deficiency state seen in the coeliac syndrome.

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Year:  1969        PMID: 5810979      PMCID: PMC1552898          DOI: 10.1136/gut.10.8.662

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  9 in total

1.  The biliary and faecal loss after parenteral 58Co vitamin B12 in man.

Authors:  J F ADAMS
Journal:  Scott Med J       Date:  1963-03       Impact factor: 0.729

2.  The excretion and distribution in the tissues of parenterally administered 58Co-vitamin B12 in normal and gastrectomized rats.

Authors:  M A BOOTH; G H SPRAY
Journal:  Br J Haematol       Date:  1962-04       Impact factor: 6.998

3.  Biliary excretion of Co60 labeled vitamin B12 in dogs.

Authors:  D A WILLIGAN; E P CRONKITE; L M MEYER; S L NOTO
Journal:  Proc Soc Exp Biol Med       Date:  1958-10

4.  Intrinsic factor and radiovitamin B12 excretion in rats.

Authors:  R GRASBECK; L RUNEBERG; K SIMONS
Journal:  Acta Physiol Scand       Date:  1959-12-12

5.  The plasma clearance and urinary excretion of parenterally administered 58Co B12.

Authors:  D L MOLLIN; W R PITNEY; S J BAKER; J E BRADLEY
Journal:  Blood       Date:  1956-01       Impact factor: 22.113

6.  Bile and vitamin B12 absorption.

Authors:  K OKUDA; R GRASBECK; B F CHOW
Journal:  J Lab Clin Med       Date:  1958-01

7.  Biliary and fecal vit. B12 excretion in man: an isotope study.

Authors:  R GRASBECK; W NYBERG; P REIZENSTEIN
Journal:  Proc Soc Exp Biol Med       Date:  1958-04

8.  THE ESTIMATION OF DEOXYRIBONUCLEIC ACID IN THE PRESENCE OF SIALIC ACID: APPLICATION TO ANALYSIS OF HUMAN GASTRIC WASHINGS.

Authors:  D N CROFT; M LUBRAN
Journal:  Biochem J       Date:  1965-06       Impact factor: 3.857

9.  Cell turnover in the rat small intestinal mucosa: an appraisal of cell loss. II. Cell loss in rats with an abnormal mucosa.

Authors:  C A Loehry; D N Croft; A K Singh; B Creamer
Journal:  Gut       Date:  1969-01       Impact factor: 23.059

  9 in total
  2 in total

1.  Small intestinal permeability. 1. Effects of ischaemia and exposure to acetyl salicylate.

Authors:  J G Kingham; P J Whorwell; C A Loehry
Journal:  Gut       Date:  1976-05       Impact factor: 23.059

2.  Gastric function and absorption of vitamin B12 in children with celiac disease.

Authors:  J Kokkonen; S Similä
Journal:  Eur J Pediatr       Date:  1979-10       Impact factor: 3.183

  2 in total

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