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Literature DB >> 58071

Endogenous ecotropic mouse type C viruses deficient in replication and production of XC plaques.

Abstract

Endogenous ecotropic type C viruses were induced by iodedeoxyuridine from nontransformed and chemically or spontaneously transformed clones of the C3H/10T1/2 cell line. Viruses produced by cells of certain transformed clones were N-tropic and formed large XC plaques. In contrast, viruses produced by nontransformed C3H/10T1/2 cells were not detectable in the XC plaque test. These XC- viruses infected mouse cells with high efficiency, as shown by the induction of murine leukemia virus group-specific antigens in infected cells, but virus production, as determined by DNA polymerase-containing particles, was extremely low. Upon growth in certain mouse cells these replication-deficient, XC(-) viruses converted to type C viruses that were similar in XC assays to N-tropic AKR virus (XC+).

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Year: 1976 PMID： 58071 PMCID： PMC515565

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

14 in total

2. A single point mutation in the envelope gene is responsible for replication and XC fusion deficiency of the endogenous ecotropic C3H/He murine leukemia virus and for its repair in culture.

Authors: G Sithanandam; U R Rapp
Journal: J Virol Date: 1988-03 Impact factor: 5.103

3. Generation of oncogenic type C viruses: rapidly leukemogenic viruses derived from C3H mouse cells in vivo and in vitro.

Authors: U R Rapp; G J Todaro
Journal: Proc Natl Acad Sci U S A Date: 1978-05 Impact factor: 11.205

4. Defective Friend spleen focus-forming virus: interfering properties and isolation free from standard leukemia-inducing helper virus.

Authors: R J Eckner; K L Hettrick
Journal: J Virol Date: 1977-10 Impact factor: 5.103

8. Replication-defective Friend murine leukemia virus particles containing uncleaved gag polyproteins and decreased levels of envelope glycoprotein.

Authors: J K Collins; B Chesebro
Journal: J Virol Date: 1981-01 Impact factor: 5.103

9. Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase.

Authors: S Goff; P Traktman; D Baltimore
Journal: J Virol Date: 1981-04 Impact factor: 5.103

10. Frequent isolation of ecotropic murine leukemia virus after x-ray irradiation of C57BL/6 mice and establishment of producer lymphoid cell lines from radiation-induced lymphomas.

Authors: P Sankar-Mistry; P Jolicoeur
Journal: J Virol Date: 1980-07 Impact factor: 5.103

Endogenous ecotropic mouse type C viruses deficient in replication and production of XC plaques.

1. Endogenous oncornaviruses in chemically induced transformation. I. Transformation independent of virus production.

2. Clonal cells lines from a feral mouse embryo which lack host-range restrictions for murine leukemia viruses.

3. Differential cellular regulation of three distinct classes of type C RNA viruses endogenous to mouse cells.

4. Plaque assay techniques for murine leukemia viruses.

5. A distinct class of inducible murine type-C viruses that replicates in the rabbit SIRC cell line.

6. Isolation of naturally occurring viruses of the murine leukemia virus group in tissue culture.

7. Host-range restrictions of murine leukemia viruses in mouse embryo cell cultures.

8. Murine leukemia virus: high-frequency activation in vitro by 5-iododeoxyuridine and 5-bromodeoxyuridine.

9. Genetic factors influencing C-type RNA virus induction.

10. Studies of genetic transmission of murine leukemia virus by AKR mice. II. Crosses with Fv-1 b strains of mice.

1. Isolation and characterization of a mouse cell line containing a defective Moloney murine leukemia virus genome.

2. A single point mutation in the envelope gene is responsible for replication and XC fusion deficiency of the endogenous ecotropic C3H/He murine leukemia virus and for its repair in culture.

3. Generation of oncogenic type C viruses: rapidly leukemogenic viruses derived from C3H mouse cells in vivo and in vitro.

4. Defective Friend spleen focus-forming virus: interfering properties and isolation free from standard leukemia-inducing helper virus.

5. The role of envelope glycoprotein processing in murine leukemia virus infection.

6. Rescue and transmission of a replication-defective variant of moloney murine leukemia virus.

7. Late-passage SC-1 cells resistant to N- and B-tropic viruses but sensitive to NB-tropic viruses.

8. Replication-defective Friend murine leukemia virus particles containing uncleaved gag polyproteins and decreased levels of envelope glycoprotein.

9. Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase.

10. Frequent isolation of ecotropic murine leukemia virus after x-ray irradiation of C57BL/6 mice and establishment of producer lymphoid cell lines from radiation-induced lymphomas.