| Literature DB >> 6155476 |
Abstract
A late-passage derivative of SC-1 cells with stable relative resistance to N- and B-tropic viruses but with retained sensitivity to NB-tropic viruses has been identified. Dual resistance was seen with the XC plaque assay, as well as reverse transcriptase assay and radioimmunoassay for viral p30. Evidence was found for resistance in clonal derivatives. These findings suggest a possible instability in determinants of cellular resistance to endogenous retroviruses and may be useful in further analysis of resistance to retrovirus infection.Entities:
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Year: 1980 PMID: 6155476 PMCID: PMC288760 DOI: 10.1128/JVI.34.3.711-715.1980
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103