Literature DB >> 5806426

The effect of heliotrine, a pyrrolizidine alkaloid, on human liver cells in culture.

S F Sullman, A J Zuckerman.   

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Year:  1969        PMID: 5806426      PMCID: PMC2072115     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


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  11 in total

1.  THE EFFECT OF CYANIDE AND AZIDE ON THE MUTAGENIC ACTIVITY OF THE PYRROLIZIDINE ALKALOID HELIOTRINE IN DROSOPHILA MELANOGASTER.

Authors:  N G BRINK
Journal:  Z Vererbungsl       Date:  1963-12-30

2.  Alkylation as the mechanism by which the hepatotoxic pyrrolizidine alkaloids act on cell nuclei.

Authors:  C C CULVENOR; A T DANN; A T DICK
Journal:  Nature       Date:  1962-08-11       Impact factor: 49.962

3.  Further observations on the subacute and chronic liver changes in rats after a single dose of various pyrrolizidine (Senecio) alkaloids.

Authors:  R SCHOENTAL; P N MAGEE
Journal:  J Pathol Bacteriol       Date:  1959-10

4.  Toxicity of pyrrolizidine alkaloids.

Authors:  A R Mattocks
Journal:  Nature       Date:  1968-02-24       Impact factor: 49.962

5.  Inhibition by lasiocarpine of RNA synthesis, RNA polymerase and induction of tryptophan pyrrolase activity.

Authors:  J Reddy; C Harris; D Svoboda
Journal:  Nature       Date:  1968-02-17       Impact factor: 49.962

6.  The ultrastructure of the enlarged hepatocytes induced in rats with a single oral dose of retrorsine, a pyrrolizidine (Senecio) alkaloid.

Authors:  B A Afzelius; R Schoental
Journal:  J Ultrastruct Res       Date:  1967-10-31

7.  Delayed hepatitis and cirrhosis in weanling rats following a single small dose of the senecio alkaloid, lasiocarpine.

Authors:  J P Nolan; R L Scheig; G Klatskin
Journal:  Am J Pathol       Date:  1966-07       Impact factor: 4.307

8.  The interaction of aflatoxins with purines and purine nucleosides.

Authors:  J I Clifford; K R Rees
Journal:  Biochem J       Date:  1967-05       Impact factor: 3.857

9.  Primary liver tumours in rats following feeding with alkaloids of Senecio jacobaea.

Authors:  J W COOK; E DUFFY; R SCHOENTAL
Journal:  Br J Cancer       Date:  1950-12       Impact factor: 7.640

10.  Senecio alkaloids; primary liver tumours in rats as a result of treatment with (1) a mixture of alkaloids from S. jacobaea Lin.; (2) retrorsine; (3) isatidine.

Authors:  R SCHOENTAL; M A HEAD; P R PEACOCK
Journal:  Br J Cancer       Date:  1954-09       Impact factor: 7.640

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  7 in total

1.  Induction of morphological changes in human embryo liver cells by the pyrrolizidine alkaloid lasiocarpine.

Authors:  S J Armstrong; A J Zuckerman; R G Bird
Journal:  Br J Exp Pathol       Date:  1972-04

2.  Further studies on the toxicity of the aflatoxins on human cell cultures.

Authors:  S F Sullman; S J Armstrong; A J Zuckerman; K R Rees
Journal:  Br J Exp Pathol       Date:  1970-06

3.  Lytic necrosis resembling peliosis hepatis produced by lasiocarpine in the mouse liver. A light and electron microscopic study.

Authors:  B H Ruebner; K Watanabe; J S Wand
Journal:  Am J Pathol       Date:  1970-08       Impact factor: 4.307

4.  Hepatic megalocytosis in chronic lasiocarpine poisoning. Some functional studies.

Authors:  D Svoboda; J Reddy; S Bunyaratvej
Journal:  Am J Pathol       Date:  1971-11       Impact factor: 4.307

5.  Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.

Authors:  Ari L Zaiman; Megan Podowski; Satya Medicherla; Kimberley Gordy; Fang Xu; Lijie Zhen; Larissa A Shimoda; Enid Neptune; Linda Higgins; Alison Murphy; Sarvajit Chakravarty; Andrew Protter; Pravin B Sehgal; Hunter C Champion; Rubin M Tuder
Journal:  Am J Respir Crit Care Med       Date:  2008-01-17       Impact factor: 21.405

6.  Hepatic veno-occlusive disease as a result of a traditional remedy: confirmation of toxic pyrrolizidine alkaloids as the cause, using an in vitro technique.

Authors:  M Zuckerman; V Steenkamp; M J Stewart
Journal:  J Clin Pathol       Date:  2002-09       Impact factor: 3.411

Review 7.  In vitro assay of cytotoxicity with cultured liver: accomplishments and possibilities.

Authors:  J W Grisham; R K Charlton; D G Kaufman
Journal:  Environ Health Perspect       Date:  1978-08       Impact factor: 9.031

  7 in total

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