Literature DB >> 580135

The relationship between circulating free and bound insulin, insulin antibodies, insulin dosage and diabetic control in insulin treated diabetics.

C M Asplin, M Hartog, D J Goldie.   

Abstract

Free and bound insulin concentrations, blood glucose and anti-insulin antibody binding characteristics have been determined in 100 insulin treated diabetics; medium serum free insulin was 11 mU/l when fasting and rose to 30 mU/l after the mid-day meal. Significant correlation between blood glucose and serum free (but not bound) insulin was found. No relationship between insulin antibodies and daily insulin dose or diabetic control were found, nor a relationship between free insulin and antibody characteristics.

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Year:  1978        PMID: 580135     DOI: 10.1530/acta.0.0870330

Source DB:  PubMed          Journal:  Acta Endocrinol (Copenh)        ISSN: 0001-5598


  3 in total

1.  Free insulin concentrations in immediately extracted plasma samples and their relationships to clinical and metabolic parameters in insulin-treated diabetic patients.

Authors:  R Giannarelli; P Marchetti; M Giannecchini; G Di Cianni; P Cecchetti; A Masoni; R Navalesi
Journal:  Acta Diabetol Lat       Date:  1988 Jul-Sep

2.  Relationship between metabolic control and HDL2-cholesterol in type I diabetic patients.

Authors:  L Beccaria; D Sommariva; F Meschi; M G Boga; A Branchi; I Pogliaghi; C Ottomano; G Chiumello
Journal:  Acta Diabetol Lat       Date:  1986 Apr-Jun

3.  Influence of insulin antibodies on pharmacokinetics and bioavailability of recombinant human and highly purified beef insulins in insulin dependent diabetics.

Authors:  R S Gray; P Cowan; U di Mario; R A Elton; B F Clarke; L J Duncan
Journal:  Br Med J (Clin Res Ed)       Date:  1985-06-08
  3 in total

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