Literature DB >> 3751447

Relationship between metabolic control and HDL2-cholesterol in type I diabetic patients.

L Beccaria, D Sommariva, F Meschi, M G Boga, A Branchi, I Pogliaghi, C Ottomano, G Chiumello.   

Abstract

The relationship of the degree of metabolic control to the serum lipoprotein pattern has been studied in 62 young insulin treated diabetic patients. Stable HbA1 and 24-h mean blood glucose, but not daily insulin dosage, were positively correlated to VLDL-TG (p less than 0.001) and negatively correlated to HDL2-C (p less than 0.05). HDL2-C was higher in patients with HbA1 less than 10% than in patients with HbA1 greater than 10%. In 13 patients, in whom an improvement of metabolic control was achieved, a significant increase of HDL2-C was recorded after three months. Our data are consistent with the view that in insulin-treated patients, good metabolic control is associated with low VLDL-TG and high HDL2-C levels.

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Year:  1986        PMID: 3751447     DOI: 10.1007/bf02624672

Source DB:  PubMed          Journal:  Acta Diabetol Lat        ISSN: 0001-5563


  27 in total

1.  Relation of high-density lipoprotein cholesterol concentration to type of diabetes and its control.

Authors:  A L Kennedy; T R Lappin; T D Lavery; D R Hadden; J A Weaver; D A Montgomery
Journal:  Br Med J       Date:  1978-10-28

2.  The correlation of arteriosclerosis obliterans with lipoproteins in insulin-dependent and non-insulin-dependent diabetes.

Authors:  K W Beach; J D Brunzell; L L Conquest; D E Strandness
Journal:  Diabetes       Date:  1979-09       Impact factor: 9.461

3.  Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study.

Authors:  M J Garcia; P M McNamara; T Gordon; W B Kannel
Journal:  Diabetes       Date:  1974-02       Impact factor: 9.461

4.  Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man.

Authors:  J D Brunzell; W R Hazzard; D Porte; E L Bierman
Journal:  J Clin Invest       Date:  1973-07       Impact factor: 14.808

5.  Reappraisal of the role of insulin in hypertriglyceridemia.

Authors:  J M Olefsky; J W Farquhar; G M Reaven
Journal:  Am J Med       Date:  1974-10       Impact factor: 4.965

6.  The effects of chlorpropamide and insulin on serum lipids, lipoproteins and fractional triglyceride removal.

Authors:  R Paisey; R S Elkeles; J Hambley; P Magill
Journal:  Diabetologia       Date:  1978-08       Impact factor: 10.122

7.  Hyperglycemia and plasma lipid levels: a prospective study of young insulin-dependent diabetic patients.

Authors:  J M Sosenko; J L Breslow; O S Miettinen; K H Gabbay
Journal:  N Engl J Med       Date:  1980-03-20       Impact factor: 91.245

8.  High density lipoprotein composition in insulin-dependent diabetes mellitus.

Authors:  R H Eckel; J J Albers; M C Cheung; P W Wahl; F T Lindgren; E L Bierman
Journal:  Diabetes       Date:  1981-02       Impact factor: 9.461

9.  Effects of therapy on plasma-high-density-lipoprotein-cholesterol concentration in diabetes mellitus.

Authors:  G D Calvert; J J Graham; T Mannik; P H Wise; R A Yeates
Journal:  Lancet       Date:  1978-07-08       Impact factor: 79.321

10.  Diurnal glucose--dependent fluctuations in glycosylated hemoglobin levels in insulin-dependent diabetes.

Authors:  D Daneman; N Luley; D J Becker
Journal:  Metabolism       Date:  1982-10       Impact factor: 8.694

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  1 in total

1.  Lecithin:cholesterol acyltransferase activity and high-density lipoprotein subfraction composition in type 1 diabetic patients with improving metabolic control.

Authors:  M J Weight; H S Coetzee; C M Smuts; M P Marais; J S Maritz; F S Hough; A J Benadé; J J Taljaard
Journal:  Acta Diabetol       Date:  1993       Impact factor: 4.280

  1 in total

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