Literature DB >> 579680

Malondialdehyde production by platelets during secondary aggregation.

D E MacFarlane, S Gardner, C Lipson, D C Mills.   

Abstract

A method is described for increasing the sensitivity of the thiobarbiturate assay for malondialdehyde by concentrating the coloured reaction product. The basal level of malondialdehyde-like material in plasma was found to be about 0.03 micrometer. Platelets synthesized malondialdehyde when stimulated by collagen or thrombin and also during the second phase of aggregation induced by ADP or adrenaline.

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Year:  1977        PMID: 579680

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN: 0340-6245            Impact factor:   5.249


  3 in total

1.  Platelets oxidative stress in Indian patients with ischemic heart disease.

Authors:  Mahdi Garelnabi; Vinod Gupta; Venkatesan Mallika; Jayashree Bhattacharjee
Journal:  J Clin Lab Anal       Date:  2010       Impact factor: 2.352

2.  Malonaldehyde formation in intact platelets is catalysed by thromboxane synthase.

Authors:  R M McMillan; D E MacIntyre; A Booth; J L Gordon
Journal:  Biochem J       Date:  1978-11-15       Impact factor: 3.857

3.  Determination of plasma malondialdehyde-like material and its clinical application in stroke patients.

Authors:  M T Santos; J Valles; J Aznar; J Vilches
Journal:  J Clin Pathol       Date:  1980-10       Impact factor: 3.411

  3 in total

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