| Literature DB >> 578725 |
E Komsta-Szumska, J Chmielnicka.
Abstract
The distribution of mercury and selenium has been examined in subcellular fractions of rat liver and kidneys in prolonged exposure to HgCl2 and Na2SeO3 administered separately and simultaneously. The molar ratio of mercury and selenium concentrations in subcellular fractions of the organs examined varied considerably. Selenium displaced mercury from the soluble kidney fraction bound mainly with metallothionein to the nonhistone protein fraction of liver nuclei. The Hg-stimulated biosynthesis of metallothionein has been eliminated under the influence of selenium.Entities:
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Year: 1977 PMID: 578725 DOI: 10.1007/bf00293656
Source DB: PubMed Journal: Arch Toxicol ISSN: 0340-5761 Impact factor: 5.153