Literature DB >> 3741138

Kidney concentrations and urinary excretion of mercury, zinc and copper following the administration of mercuric chloride and sodium selenite to rats.

J Chmielnicka, E Brzeźnicka, A Sniady.   

Abstract

The effect of single (SC) administration of mercuric chloride (1 mg Hg/kg) alone or jointly with (PO) sodium selenite (0.39 mg Se/kg) on kidney disposition of mercury (Hg) and metallothionein (MT) and urinary excretion of Hg, zinc (Zn) and copper (Cu) has been studied in the female rat. The excretion of Hg and essential metals was determined every day following exposure. Daily excretion of endogenous Cu and Zn the Hg-exposed group was about threefold and fourfold, respectively, in comparison with control groups of rats. Sodium selenite prevented the urinary excretion of endogenous Cu and partly of Zn.

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Year:  1986        PMID： 3741138     DOI： 10.1007/bf00263951

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  31 in total

1.  Enzymes of renal origin in urine as indicators of nephrotoxicity.

Authors:  W E Stroo; J B Hook
Journal:  Toxicol Appl Pharmacol       Date:  1977-03       Impact factor: 4.219

2.  A modified procedure for determination of metallothionein-like proteins in animal tissues.

Authors:  A J Zelazowski; J K Piotrowski
Journal:  Acta Biochim Pol       Date:  1977       Impact factor: 2.149

3.  [Urinary gamma-glutamyl transferase in renal toxicology of the rat. Bases of its use and significance in acute mercurial nephritis].

Authors:  J P Braun; A G Rico; P Benard; V Burgat-Sacaze; B Eghbali; J C Godfrain
Journal:  Toxicology       Date:  1978-09       Impact factor: 4.221

4.  Organ and subcellular distribution of mercury in rats in the presence of cadmium, zinc, copper, and sodium selenite.

Authors:  E Komsta-Szumska; J Chmielnicka
Journal:  Clin Toxicol       Date:  1981-11       Impact factor: 4.467

5.  Urinary and fecal excretion of selenium (Na2 75SeO3) and mercury (203Hg Cl2) administered separately and simultaneously to mice.

Authors:  P Kristensen; J C Hansen
Journal:  Toxicology       Date:  1980       Impact factor: 4.221

6.  The tissue disposition of zinc and copper following repeated administration of cadmium and selenium to rats.

Authors:  J Chmielnicka; E M Bem; E A Brzeźnicka; M Kasperek
Journal:  Environ Res       Date:  1985-08       Impact factor: 6.498

7.  Urinary metallothionein and tissue metal levels of rats injected with cadmium, mercury, lead, copper or zinc.

Authors:  Y H Lee; Z A Shaikh; C Tohyama
Journal:  Toxicology       Date:  1983 Jul-Aug       Impact factor: 4.221

8.  Changes in rat renal cortex, isolated plasma membranes and urinary enzymes following the injection of mercuric chloride.

Authors:  S A Kempson; B G Ellis; R G Price
Journal:  Chem Biol Interact       Date:  1977-08       Impact factor: 5.192

9.  Interaction of alkylmercuric compounds with sodium selenite. I. Metabolism of ethylmercuric chloride administered alone and in combination with sodium selenite in rats.

Authors:  E A Brzeźnicka; J Chmielnicka
Journal:  Environ Health Perspect       Date:  1981-06       Impact factor: 9.031

10.  Interaction of alkylmercuric compounds with sodium selenite. III. Biotransformation, levels of metallothioneinlike proteins and endogenous copper in some tissues of rats exposed to methyl or ethylmercuric chloride with and without sodium selenite.

Authors:  E A Brzeźnicka; J Chmielnicka
Journal:  Environ Health Perspect       Date:  1985-05       Impact factor: 9.031
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  6 in total

1.  Dose-dependent elimination kinetics for mercury in urine: observations in subjects with brief but high-level exposure.

Authors:  L Barregàrd; G Quelquejeu; G Sällsten; J M Haguenoer; C Nisse
Journal:  Int Arch Occup Environ Health       Date:  1996       Impact factor: 3.015

Review 2.  Biomarkers of mercury toxicity: Past, present, and future trends.

Authors:  Vasco Branco; Sam Caito; Marcelo Farina; João Teixeira da Rocha; Michael Aschner; Cristina Carvalho
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2017-04-05       Impact factor: 6.393

3.  Increased urinary excretion of zinc and copper by mercuric chloride injection in rats.

Authors:  X Liu; G F Nordberg; T Jin
Journal:  Biometals       Date:  1992       Impact factor: 2.949

4.  Comparison of the protection given by selenite, selenomethionine and biological selenium against the renotoxicity of mercury.

Authors:  L Magos; T W Clarkson; S Sparrow; A R Hudson
Journal:  Arch Toxicol       Date:  1987-08       Impact factor: 5.153

5.  Zinc-selenium interaction in the rat.

Authors:  J Chmielnicka; G Zareba; M Witasik; E Brzeźnicka
Journal:  Biol Trace Elem Res       Date:  1988 Jan-Apr       Impact factor: 3.738

6.  Effects of simultaneous low-level dietary supplementation with inorganic and organic selenium on whole-body, blood, and organ levels of toxic metals in mice.

Authors:  O Andersen; J B Nielsen
Journal:  Environ Health Perspect       Date:  1994-09       Impact factor: 9.031
  6 in total

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