Literature DB >> 578708

Levels of sulfhydryls and sulfhydryl-containing enzymes in brain, liver and testis of manganese treated rats.

G S Shukla, S V Chandra.   

Abstract

The effect of manganese on sulfhydryls and sulfhydryl-containing enzymes in brain, liver and testis of rats was investigated. Manganese produced lowering in the contents of non-protein sulfhydryl groups and inhibited the activity of glucose-6-phosphate dehydrogenase and glutathione reductase in these tissues. The contents of the metal increased significantly in brain, liver and testis of manganese administered rats. The significance of these findings is discussed.

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Year:  1977        PMID: 578708     DOI: 10.1007/bf00330824

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN: 0340-5761            Impact factor:   5.153


  10 in total

1.  Histochemical alterations in rabbit testis produced by manganese chloride.

Authors:  Z Imam; S V Chandra
Journal:  Toxicol Appl Pharmacol       Date:  1975-06       Impact factor: 4.219

2.  Manganese poisoning in Moroccan miners.

Authors:  J RODIER
Journal:  Br J Ind Med       Date:  1955-01

3.  The general pharmacology of the heavy metals.

Authors:  H PASSOW; A ROTHSTEIN; T W CLARKSON
Journal:  Pharmacol Rev       Date:  1961-06       Impact factor: 25.468

4.  Manganese in health and disease.

Authors:  G C COTZIAS
Journal:  Physiol Rev       Date:  1958-07       Impact factor: 37.312

5.  Chelation in metal intoxication II: In vitro and in vivo effect of some compounds on brain, liver, and testis of rats treated with manganese sulphate.

Authors:  J Singh; S V Chandra; S K Tandon
Journal:  Bull Environ Contam Toxicol       Date:  1975-10       Impact factor: 2.151

6.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 7.  The pharmacology of mercury compounds.

Authors:  T W Clarkson
Journal:  Annu Rev Pharmacol       Date:  1972       Impact factor: 13.820

8.  Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent.

Authors:  J Sedlak; R H Lindsay
Journal:  Anal Biochem       Date:  1968-10-24       Impact factor: 3.365

9.  Determination of manganese in blood and other tissues.

Authors:  S P Srivastava; K P Pandya; S H Zaidi
Journal:  Analyst       Date:  1969-09       Impact factor: 4.616

10.  Manganese induced hepatic lesions in carbon tetrachloride pretreated rats.

Authors:  S V Chandra; D K Saxena
Journal:  Exp Pathol (Jena)       Date:  1975
  10 in total
  2 in total

1.  Physiological model for the pharmacokinetics of cis-dichlorodiammineplatinum (II) (DDP) in the tumored rat.

Authors:  F F Farris; F G King; R L Dedrick; C L Litterst
Journal:  J Pharmacokinet Biopharm       Date:  1985-02

2.  Changes in the redox state of neuroblastoma cells after manganese exposure.

Authors:  H Eriksson; E Heilbronn
Journal:  Arch Toxicol       Date:  1983-09       Impact factor: 5.153

  2 in total

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