Literature DB >> 5778938

Pituitary polypeptide with hypoglycaemic action in diabetes mellitus.

J M Armstrong, J Bornstein, F M Ng, H P Taft.   

Abstract

A polypeptide isolated by the hydrolysis of growth hormone, studied in five patients with diabetes mellitus, has been shown able to produce hypoglycaemia, presumably by modifying the anti-insulin action of pituitary growth hormone. Possibly this substance may be suitable for treating cases of insulin resistance or when a circulating inhibitor of glucose uptake is present.

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Year:  1969        PMID： 5778938      PMCID： PMC1982955          DOI： 10.1136/bmj.2.5650.157

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  3 in total

1.  Insulin antagonists in blood of juvenile diabetics with arterial disease.

Authors:  J BORNSTEIN; D HYDE
Journal:  Diabetes       Date:  1959 Mar-Apr       Impact factor: 9.461

2.  Pituitary peptides with direct action on the metabolism of carbohydates and fatty acids.

Authors:  J Bornstein; M E Krahl; L B Marshall; M K Gould; J M Armstrong
Journal:  Biochim Biophys Acta       Date:  1968-02-01

3.  The effect of a growth hormone fraction on the activities of glyceraldehyde-3-phosphate dehydrogenase.

Authors:  J Bornstein; J M Armstrong; M D Jones
Journal:  Biochim Biophys Acta       Date:  1968-02-01
  3 in total
  4 in total

1.  [Metabolic actions of the somatropic hormone].

Authors:  L Adezati
Journal:  Acta Diabetol Lat       Date:  1971 May-Jun

2.  Growth hormone and diabetes.

Authors: 
Journal:  Br Med J       Date:  1971-01-23

3.  Potentiation of insulin action in normal subjects by a pituitary polypeptide.

Authors:  J Bornstein; J M Armstrong; F M Ng; H P Taft
Journal:  Br Med J       Date:  1969-08-23

4.  Insulin antagonist of pituitary origin in plasma of normal and diabetic subjects.

Authors:  P Zimmet; F M Ng; J Bornstein; J M Armstrong; H P Taft
Journal:  Br Med J       Date:  1971-01-23
  4 in total

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