Literature DB >> 5541231

Insulin antagonist of pituitary origin in plasma of normal and diabetic subjects.

P Zimmet, F M Ng, J Bornstein, J M Armstrong, H P Taft.   

Abstract

Studies on ultrafiltrates of the plasma of normal and diabetic subjects have shown that a polypeptide of similar characteristics to the growth-hormone-derived polypeptide In-G is present in higher concentrations in diabetic subjects, thus indicating a possible role in the pathogenesis of diabetes mellitus. The polypeptide is absent from the plasma of hypophysectomized diabetic patients.

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Year:  1971        PMID： 5541231      PMCID： PMC1794829          DOI： 10.1136/bmj.1.5742.203

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  5 in total

1.  Mechanism of the diabetogenic action of growth hormone. II. Effect of polypeptides derived from growth hormone on fat metabolism.

Authors:  J Bornstein; W M Taylor; L B Marshall; J M Armstrong; M K Gould
Journal:  Biochim Biophys Acta       Date:  1969-11-18

2.  Mechanism of the diabetogenic action of growth hormone. I. Effect of polypeptides derived from growth hormone on glycolysis in muscle.

Authors:  J Bornstein; J M Armstrong; M K Gould; J A Harcourt; M D Jones
Journal:  Biochim Biophys Acta       Date:  1969-11-18

3.  The effect of a growth hormone fraction on the activities of glyceraldehyde-3-phosphate dehydrogenase.

Authors:  J Bornstein; J M Armstrong; M D Jones
Journal:  Biochim Biophys Acta       Date:  1968-02-01

4.  Pituitary polypeptide with hypoglycaemic action in diabetes mellitus.

Authors:  J M Armstrong; J Bornstein; F M Ng; H P Taft
Journal:  Br Med J       Date:  1969-04-19

5.  Potentiation of insulin action in normal subjects by a pituitary polypeptide.

Authors:  J Bornstein; J M Armstrong; F M Ng; H P Taft
Journal:  Br Med J       Date:  1969-08-23
  5 in total
  2 in total

1.  [Metabolic actions of the somatropic hormone].

Authors:  L Adezati
Journal:  Acta Diabetol Lat       Date:  1971 May-Jun

2.  Stimulatory effect of serum from diabetic patients on insulin release from mouse pancreatic islets maintained in tissue culture.

Authors:  J H Nielsen; C Eff; T Deckert; A Andersson
Journal:  Diabetologia       Date:  1981       Impact factor: 10.122
  2 in total

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