| Literature DB >> 5778022 |
Abstract
Deoxyribonucleic acid methylase activity has been detected in a preparation of disrupted nuclei prepared from pea seedlings. S-Adenosyl-L-methionine acted as a donor of methyl groups, and the product of the reaction was identified as 5-methylcytosine. The reaction had a sharp temperature optimum at about 30 degrees C and was unusual in that the DNA methylase was able to methylate DNA in the crude extract.Entities:
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Year: 1969 PMID: 5778022 DOI: 10.1126/science.164.3880.721
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728