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Literature DB >> 5773113

Alcohol and amitriptyline effects on skills related to driving behavior.

Abstract

Three motor-skill tests related to driving ability were given to 21 healthy young volunteers after administration of various combinations of amitriptyline, placebo, and alcohol. It was found that the tricylic antidepressant added to the deleterious effects of alcohol.

Entities: Chemical

Mesh：

Substances：

Year: 1969 PMID： 5773113 DOI： 10.1126/science.163.3874.1467

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

14 in total

1. Drugs and driving.

Authors: T Silverstone
Journal: Br J Clin Pharmacol Date: 1974-12 Impact factor: 4.335

2. Clobazam, a 1,5-benzodiazepine, and car-driving ability.

Authors: I Hindmarch; G W Hanks; A J Hewett
Journal: Br J Clin Pharmacol Date: 1977-10 Impact factor: 4.335

3. [Complex effects of different factors (noise, tranquilizer, difficult working condition, test time) on pursuit tracking performance and beat-to-beat heart rate behavior (author's transl)].

Authors: H Strasser; W Müller-Limmroth
Journal: Int Arch Arbeitsmed Date: 1973-05-23

Review 4. Low blood alcohol concentrations and driving impairment. A review of experimental studies and international legislation.

Authors: S D Ferrara; S Zancaner; R Giorgetti
Journal: Int J Legal Med Date: 1994 Impact factor: 2.686

Review 5. Drugs, alcohol and driving.

Authors: T Seppala; M Linnoila; M J Mattila
Journal: Drugs Date: 1979-05 Impact factor: 9.546

6. Effects of zimeldine, mianserin and amitriptyline on psychomotor skills and their interaction with ethanol a placebo controlled cross-over study.

Authors: T Seppälä; C Strömberg; I Bergman
Journal: Eur J Clin Pharmacol Date: 1984 Impact factor: 2.953

Alcohol and amitriptyline effects on skills related to driving behavior.

1. Drugs and driving.

2. Clobazam, a 1,5-benzodiazepine, and car-driving ability.

3. [Complex effects of different factors (noise, tranquilizer, difficult working condition, test time) on pursuit tracking performance and beat-to-beat heart rate behavior (author's transl)].

Review 4. Low blood alcohol concentrations and driving impairment. A review of experimental studies and international legislation.

Review 5. Drugs, alcohol and driving.

6. Effects of zimeldine, mianserin and amitriptyline on psychomotor skills and their interaction with ethanol a placebo controlled cross-over study.

7. Ethanol effects on brain concentrations of amitriptyline and the relationship to psychomotor function.

8. An evaluation of possible interactions between ethanol and trazodone or amitriptyline.

9. Amitriptyline and ethanol: pharmacokinetic and pharmacodynamic interaction.

10. Antidepressant drugs and ethanol: behavioral and pharmacokinetic interactions in mice.