Literature DB >> 8038109

Low blood alcohol concentrations and driving impairment. A review of experimental studies and international legislation.

S D Ferrara1, S Zancaner, R Giorgetti.   

Abstract

While noting that there is no international scientific or legislative uniformity in blood alcohol concentration (BAC) levels admissible for driving motor vehicles, the authors analyse problems concerning the effects of low levels of ethyl alcohol on driving ability. A summary of the international literature on this subject reveals: the existence of contrasting assumptions, with scientific evidence clearly demonstrating altered psychomotor functions; the need to adopt sufficiently complex psychometric tests to reveal the effects of low BACs; the need to improve standardization of experimental studies on man-machine interaction; the need to investigate the following areas: tolerance to alcohol; low BACs with inexperienced, infrequent drinkers and chronic, heavy drinkers; hangover effects; alcohol-gender-age interactions, and specific effects on young drivers; alcohol-drug combinations. The analysis of legislation and enforcement policies also reveals the need for: re-evaluation of the international legal BAC threshold and standardization of procedures for ascertaining the degree of driving disability; further scientific research to compare and evaluate selected legislative initiatives currently in place in most states; to identify the best strategies and procedures to detect and arrest impaired drivers; to determine the optimum random testing rate to maximize deterrent effects in the workplace at minimal cost; to design innovative and comprehensive approaches to rehabilitation programs needed for subgroups of offenders and of workers; to study the effectiveness of new legislations and policies.

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Year:  1994        PMID: 8038109     DOI: 10.1007/bf01371332

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  70 in total

1.  Two weeks' treatment with chlorpromazine, thioridazine, sulpiride, or bromazepam: actions and interactions with alcohol on psychomotor skills related to driving.

Authors:  T Seppälä; I Saario; M J Mattila
Journal:  Mod Probl Pharmacopsychiatry       Date:  1976

2.  Immediate and overnight effects of zopiclone 7.5 mg and nitrazepam 5 mg with ethanol, on psychomotor performance and memory in healthy volunteers.

Authors:  I Hindmarch
Journal:  Int Clin Psychopharmacol       Date:  1990-04       Impact factor: 1.659

3.  The pharmacodynamics of ethanol: effects on performance and judgment.

Authors:  F M Gengo; C Gabos; C Straley; C Manning
Journal:  J Clin Pharmacol       Date:  1990-08       Impact factor: 3.126

Review 4.  Neuronal mechanisms of ethanol sensitivity.

Authors:  K Kiianmaa
Journal:  Alcohol Alcohol       Date:  1990       Impact factor: 2.826

5.  The interactive effects of alcohol and mood on dual-task performance.

Authors:  C Miles; K Porter; D M Jones
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

6.  Effect of alcohol on visual constancy values and possible relation to driving performance.

Authors:  T Farrimond
Journal:  Percept Mot Skills       Date:  1990-02

7.  A microanalysis of ethanol-induced disruption of body sway and psychomotor performance in women.

Authors:  S E Lukas; B W Lex; J P Slater; N E Greenwald; J H Mendelson
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

8.  Expectancy and tolerance: a study of acute alcohol intoxication using the balanced placebo design.

Authors:  J C Laberg; T Löberg
Journal:  J Stud Alcohol       Date:  1989-09

9.  Skills performance at low blood alcohol levels.

Authors:  H Moskowitz; M M Burns; A F Williams
Journal:  J Stud Alcohol       Date:  1985-11

10.  Effects of acute aspartame and acute alcohol ingestion upon the cognitive performance of pilots.

Authors:  A F Stokes; A Belger; M T Banich; H Taylor
Journal:  Aviat Space Environ Med       Date:  1991-07
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  7 in total

Review 1.  GABAergic contributions to alcohol responsivity during adolescence: insights from preclinical and clinical studies.

Authors:  Marisa M Silveri
Journal:  Pharmacol Ther       Date:  2014-03-11       Impact factor: 12.310

2.  Effects of repeated 3,4-methylenedioxymethamphetamine administration on neurotransmitter efflux and sensory-evoked discharge in the ventral posterior medial thalamus.

Authors:  M A Starr; M E Page; B D Waterhouse
Journal:  J Pharmacol Exp Ther       Date:  2011-10-07       Impact factor: 4.030

3.  A cost analysis of web-enhanced training to reduce alcohol sales to intoxicated bar patrons.

Authors:  Timothy F Page; Dawn M Nederhoff; Alexandra M Ecklund; Keith J Horvath; Toben F Nelson; Darin J Erickson; Traci L Toomey
Journal:  J Alcohol Drug Educ       Date:  2015-08

4.  Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla.

Authors:  Rosane Gomez; Kevin L Behar; June Watzl; Stuart A Weinzimer; Barbara Gulanski; Gerard Sanacora; Julia Koretski; Elizabeth Guidone; Lihong Jiang; Ismene L Petrakis; Brian Pittman; John H Krystal; Graeme F Mason
Journal:  Biol Psychiatry       Date:  2011-08-19       Impact factor: 13.382

5.  Estimation of the Potential Effectiveness of Lowering the Blood Alcohol Concentration (BAC) Limit for Driving from 0.08 to 0.05 Grams per Deciliter in the United States.

Authors:  James C Fell; Michael Scherer
Journal:  Alcohol Clin Exp Res       Date:  2017-10-24       Impact factor: 3.455

6.  The effectiveness of a 0.05 blood alcohol concentration (BAC) limit for driving in the United States.

Authors:  James C Fell; Robert B Voas
Journal:  Addiction       Date:  2013-10-25       Impact factor: 6.526

Review 7.  Medical marijuana and driving: a review.

Authors:  Mark J Neavyn; Eike Blohm; Kavita M Babu; Steven B Bird
Journal:  J Med Toxicol       Date:  2014-09
  7 in total

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