Literature DB >> 5759918

Evidence for excision of ultraviolet-induced pyrimidine dimers from the DNA of human cells in vitro.

J D Regan, J E Trosko, W L Carrier.   

Abstract

Within 12-24 hr after human cells were irradiated with ultraviolet light, approximately 50% of the ultraviolet-induced pyrimidine dimers were lost from the DNA. Pyrimidine dimers were found in the TCA-soluble fraction of ultraviolet-irradiated cells at 24 hr. Excess thymidine, caffeine, or hydroxyurea had no effect on the loss of pyrimidine dimers from the DNA of ultraviolet-irradiated cells.

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Year:  1968        PMID： 5759918      PMCID： PMC1367338          DOI： 10.1016/S0006-3495(68)86490-2

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  12 in total

1.  Amino acid metabolism in mammalian cell cultures.

Authors:  H EAGLE
Journal:  Science       Date:  1959-08-21       Impact factor: 47.728

2.  THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM.

Authors:  R B SETLOW; W L CARRIER
Journal:  Proc Natl Acad Sci U S A       Date:  1964-02       Impact factor: 11.205

3.  Triploidy in human cell line.

Authors:  J D Regan; J B Smith
Journal:  Science       Date:  1965-09-24       Impact factor: 47.728

4.  Evidence for dark-reactivation of ultraviolet light damage in mouse L cells.

Authors:  A M Rauth
Journal:  Radiat Res       Date:  1967-05       Impact factor: 2.841

5.  The relationship between the rate of DNA synthesis and its inhibition by ultraviolet light in mammalian cells.

Authors:  J E Cleaver
Journal:  Radiat Res       Date:  1967-04       Impact factor: 2.841

6.  Inhibition of DNA synthesis in HeLa cells by hydroxyurea.

Authors:  S E Pfeiffer; L J Tolmach
Journal:  Cancer Res       Date:  1967-01       Impact factor: 12.701

7.  Thymine dimerization in L-strain mammalian cells after irradiation with ultraviolet light and the search for repair mechanisms.

Authors:  M Klímek
Journal:  Photochem Photobiol       Date:  1966-08       Impact factor: 3.421

8.  Induction of thymine dimers in synchronized populations of Chinese hamster cells.

Authors:  D L Steward; R M Humphrey
Journal:  Nature       Date:  1966-10-15       Impact factor: 49.962

9.  Responses of synchronous populations of HeLa cells to ultraviolet irradiation at selected stages of the generation cycle.

Authors:  B Djordjevic; L J Tolmach
Journal:  Radiat Res       Date:  1967-10       Impact factor: 2.841

10.  Mechanism of the cytotoxic action of alkylating agents in mammalian cells and evidence for the removal of alkylated groups from deoxyribonucleic acid.

Authors:  A R Crathorn; J J Roberts
Journal:  Nature       Date:  1966-07-09       Impact factor: 49.962
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  48 in total

1.  Implications of somatic recombination and sister chromatid exchange in Bloom's syndrome and cells treated with mitomycin C.

Authors:  D E Comings
Journal:  Humangenetik       Date:  1975-07-23

2.  Postreplication repair of ultraviolet damage to DNA, DNA-chain elongation, and effects of metabolic inhibitors in mouse L cells.

Authors:  Y Fujiwara
Journal:  Biophys J       Date:  2009-01-01       Impact factor: 4.033

3.  Distribution of sensitivity to 4-nitroquinoline 1-oxide among Japanese lymphoblastoid cell lines.

Authors:  C Kiyohara; T Hirohata; M Kuratsune; J Nagayama
Journal:  Bull Environ Contam Toxicol       Date:  1991-01       Impact factor: 2.151

4.  Nonuniform distribution of DNA repair in chromatin after treatment with methyl methanesulfonate.

Authors:  W J Bodell
Journal:  Nucleic Acids Res       Date:  1977-08       Impact factor: 16.971

5.  Significance of dimers to the size of newly synthesized DNA in UV-irradiated Chinese hamster ovary cells.

Authors:  J M Clarkson; R R Hewitt
Journal:  Biophys J       Date:  1976-10       Impact factor: 4.033

6.  Effect of caffeine on postreplication repair in human cells.

Authors:  S N Buhl; J D Regan
Journal:  Biophys J       Date:  1974-07       Impact factor: 4.033

7.  [Excision repair in lymphocytes of psoriasis (author's transl)].

Authors:  E Bohnert; E G Jung
Journal:  Arch Dermatol Forsch       Date:  1975

8.  Effect of caffeine on DNA synthesis in mammalian cells.

Authors:  A R Lehmann
Journal:  Biophys J       Date:  1972-10       Impact factor: 4.033

9.  High blood pressure related to carcinogen-induced unscheduled DNA synthesis, DNA carcinogen binding, and chromosomal aberrations in human lymphocytes.

Authors:  R W Pero; C Bryngelsson; F Mitelman; T Thulin; A Nordén
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205

10.  DNA chain elongation and joining in normal human and xeroderma pigmentosum cells after ultraviolet irradiation.

Authors:  S N Buhl; R M Stillman; R B Setlow; J D Regan
Journal:  Biophys J       Date:  1972-09       Impact factor: 4.033
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