Literature DB >> 198747

Nonuniform distribution of DNA repair in chromatin after treatment with methyl methanesulfonate.

W J Bodell.   

Abstract

The distribution of methyl methanesulfonate induced DNA repair was measured in mouse mammary cell chromatin by digestion of "repair labeled" nuclei with micrococcal nuclease. The results indicate that there is a nonuniform distribution of DNA repair in chromatin. The chromatin fraction digested during the first 5 minutes of incubation with micrococcal nuclease appears to be a primary site of DNA repair after methyl methanesulfoante treatment. The observed nonuniform distribution of DNA repair in chromatin may be due to 1)a nonrandom alkylation of DNA in chromatin by methyl methanesulfonate or 2)areas in chromatin of increased accessibility for the repair enzymes to the DNA lesions.

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Year:  1977        PMID： 198747      PMCID： PMC342596          DOI： 10.1093/nar/4.8.2619

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  42 in total

1.  Chromosomal aberrations in irradiated and nitrogen mustard-treated mice.

Authors:  K G STEVENSON; H J CURTIS
Journal:  Radiat Res       Date:  1961-12       Impact factor: 2.841

2.  Preferential location of chlorambucil-induced breakage in the chromosomes of normal human lymphocytes.

Authors:  B R Reeves; C Margoles
Journal:  Mutat Res       Date:  1974-06       Impact factor: 2.433

3.  Spheroid chromatin units (v bodies).

Authors:  A L Olins; D E Olins
Journal:  Science       Date:  1974-01-25       Impact factor: 47.728

4.  The localisation of radiation induced chromosome aberrations in relation to the distribution of heterochromatin in Secale cereale.

Authors:  A T Natarajan; G Ahnström
Journal:  Chromosoma       Date:  1970       Impact factor: 4.316

5.  Specific sites of interaction between histones and DNA in chromatin.

Authors:  R Axel; W Melchior; B Sollner-Webb; G Felsenfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205

6.  On the possibility that DNA repair is related to age in non-dividing cells.

Authors:  K T Wheeler; J T Lett
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

7.  Requirement for cell replication in the fixation and expression of the transformed state in mouse cells treated with 4-nitroquinoline-1-oxide.

Authors:  T Kakunaga
Journal:  Int J Cancer       Date:  1974-12-15       Impact factor: 7.396

8.  Comparative studies of host-cell reactivation, colony forming ability and excision repair after UV irradiation of xeroderma pigmentosum, normal human and some other mammalian cells.

Authors:  H Takebe; S Nii; M I Ishii; H Utsumi
Journal:  Mutat Res       Date:  1974-12       Impact factor: 2.433

9.  Reduced DNA repair in mouse satellite DNA after treatment with methylmethanesulfonate, and N-methyl-N-nitrosourea.

Authors:  W J Bodell; M R Banerjee
Journal:  Nucleic Acids Res       Date:  1976-07       Impact factor: 16.971

10.  DNA repair in Potorous tridactylus.

Authors:  S N Buhl; R B Setlow; J D Regan
Journal:  Biophys J       Date:  1974-10       Impact factor: 4.033
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  13 in total

Review 1.  Evolutionary consequences of nonrandom damage and repair of chromatin domains.

Authors:  T Boulikas
Journal:  J Mol Evol       Date:  1992-08       Impact factor: 2.395

Review 2.  [The role of enzymatic DNA repair in carcinogenesis and cancer chemotherapy].

Authors:  E Harbers
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-08-24

3.  Implication of localization of human DNA repair enzyme O6-methylguanine-DNA methyltransferase at active transcription sites in transcription-repair coupling of the mutagenic O6-methylguanine lesion.

Authors:  R B Ali; A K Teo; H K Oh; L S Chuang; T C Ayi; B F Li
Journal:  Mol Cell Biol       Date:  1998-03       Impact factor: 4.272

4.  Distribution of DNA damage in chromatin and its relation to repair in human cells treated with 7-bromomethylbenz(a) anthracene.

Authors:  F B Oleson; B L Mitchell; A Dipple; M W Lieberman
Journal:  Nucleic Acids Res       Date:  1979-11-10       Impact factor: 16.971

Review 5.  Mechanisms of transcription-repair coupling and mutation frequency decline.

Authors:  C P Selby; A Sancar
Journal:  Microbiol Rev       Date:  1994-09

6.  Transient conformation changes in chromatin during excision repair of ultraviolet damage to DNA.

Authors:  W J Bodell; J E Cleaver
Journal:  Nucleic Acids Res       Date:  1981-01-10       Impact factor: 16.971

Review 7.  Cellular and molecular aspects of immune system aging.

Authors:  D L Doggett; M P Chang; T Makinodan; B L Strehler
Journal:  Mol Cell Biochem       Date:  1981-07       Impact factor: 3.396

8.  The distribution of DNA repair synthesis in chromatin and its rearrangement following damage with N-acetoxy-2-acetylaminofluorene.

Authors:  T D Tlsty; M W Lieberman
Journal:  Nucleic Acids Res       Date:  1978-09       Impact factor: 16.971

9.  DNA cleavage in chromatin spacer segments by a non-enzymic probe, 1,10-phenanthroline-copper complex.

Authors:  M Skalka; M Cejková
Journal:  Mol Biol Rep       Date:  1985-04       Impact factor: 2.316

10.  The use of radioimmunoassay to study the formation and disappearance of O6-methylguanine in mouse liver satellite and main-band DNA following dimethylnitrosamine administration.

Authors:  S A Kyrtopoulos; P F Swann
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553
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