Literature DB >> 575578

Effect of bilirubin on the fungicidal capacity of human neutrophils.

Y H Thong, D Ness, A Ferrante.   

Abstract

The effect of unconjugated bilirubin on the fungicidal capacity of human neutrophils was examined. Per cent Torulopsis glabrata killed in the presence of 1 x 10(-5) and 5 x 10(-5) M bilirubin was 72.7 +/- 2.5 and 40.9 +/- 7.2 respectively, compared to 81.4 +/- 4.1 in control (p less than 0.01 and p less than 0.001), respectively). This effect was not due to a concomitant inhibition of phagocytosis. The results suggest that jaundiced neonates may be more susceptible to fungal infections.

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Year:  1979        PMID: 575578     DOI: 10.1080/00362177985380171

Source DB:  PubMed          Journal:  Sabouraudia        ISSN: 0036-2174


  11 in total

Review 1.  The immunosuppressive effects of bilirubin.

Authors:  V Vĕtvicka; P Síma; I Miler; M Bilej
Journal:  Folia Microbiol (Praha)       Date:  1991       Impact factor: 2.099

2.  The stimulatory effect of bilirubin on phagocytic activity.

Authors:  M Bilej; V Vĕtvicka; P Síma
Journal:  Folia Microbiol (Praha)       Date:  1989       Impact factor: 2.099

3.  The in vitro cytotoxic effect of bilirubin on human lymphocytes and granulocytes.

Authors:  I Miler; M Indrová; J Bubeník; J Vondrácek
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099

4.  The effect of bilirubin on the Fc receptor expression and phagocytic activity of mouse peritoneal macrophages.

Authors:  V Vĕtvicka; I Miler; P Síma; L Táborský; L Fornůsek
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099

5.  Bilirubin inhibits the chemotactic activity of human polymorphonuclear leukocytes in vitro.

Authors:  I Miler; J Vondrácek; L Hromádková
Journal:  Folia Microbiol (Praha)       Date:  1981       Impact factor: 2.099

6.  The suppressive effect of continuous infusion of bilirubin on the immune response in mice.

Authors:  P Síma; J Malá; I Miler; R Hodr; E Truxová
Journal:  Folia Microbiol (Praha)       Date:  1980       Impact factor: 2.099

7.  The effect of bilirubin on the phagocytic activity of mouse peripheral granulocytes and monocytes in vivo.

Authors:  I Miler; V Vĕtvicka; P Síma; L Táborský
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099

8.  Conditioned medium from stimulated mononuclear leukocytes augments human neutrophil-mediated killing of a virulent Acanthamoeba sp.

Authors:  A Ferrante; T J Abell
Journal:  Infect Immun       Date:  1986-02       Impact factor: 3.441

9.  Intracellular accumulation of unconjugated bilirubin inhibits phytohemagglutin-induced proliferation and interleukin-2 production of human lymphocytes.

Authors:  Y Haga; M A Tempero; D Kay; R K Zetterman
Journal:  Dig Dis Sci       Date:  1996-07       Impact factor: 3.199

10.  The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.

Authors:  Dora Brites
Journal:  Front Pharmacol       Date:  2012-05-29       Impact factor: 5.810

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